Stephanie, generally, I have patients take 20 to 150mg a day for sleep +/- anxiety. Start low and go slow. Know the dosages of your product. Usually 2/3 to 3/4 of the daily dose is 1-2 hours before bedtime, and the other portion is upon waking (to improve wakefulness during the day). Other factors such as stress, hormone replacement, other meds & medical conditions, etc. play a role along with individual differences. I own a compounding pharmacy, so we see a lot of unique needs. I can't give more specific advice in this forum, but there is help!
Look up Chris Shade (quicksilver scientific) on YouTube, specifically a webinar entitled ‘Cannabidiol: The Full Story pt.2’. He is a brilliant biochemist who has been studying the biochemical effects of cannabidiol. He says that CBD has the potential to be more therapeutic than THC as it up-regulates/down-regulates gene expression in over 400 genes each way (up and down). A great balancer and extremely helpful in treating Lyme, more specifically allowing for more aggressive detoxification of the Lyme and co-infections. There is also considerably symbiosis with heavy metals, molds, EMF’s, etc. so you must also address those aspects. It’s supremely complex and even most Lyme literate docs don’t deal with all aspects. Antibiotics are often counterproductive with persistent Lyme as the spirochetes protect themselves with a biofilm that must be broken down (Interfase Plus). Protocols must be comprehensive in order to make progress. If you have not checked your CD57, do that. It’s a marker for natural killer cells commonly associated with Lyme (a simplistic explanation). The reference range is 100-300. First time I had it checked 2 years ago, it was 48. Despite modest attempts to boost my CD57 with some of the Nutramedix products, I only got 6-7 point increase per year. In April of this year, I got more aggressive with a homeopathic regimen, taking a variety of the Cowden (Nutramedix), Buhner and other products. The next time I checked CD57, two months later, it jumped 70 points… remarkable by any measure. My western blot also went from 2 bands to 5 bands as my body as finally able to mount an antibody response. I can’t say for sure which products had the biggest impact, but if I had to guess, it would be the Biocidin LSF (liposomal) and perhaps DesBio Lyme Plus. But I was also taking Samento, Burbur, Cumanda, resveratrol, glutathione, phosphatidylcholine, NanoMojo, and a variety of other things and a good supplement regimen. There is no one product answer. Cannabinoids can help with the symptoms and support a more aggressive regimen, but addressing the Lyme must be a multi-faceted effort. Be very wary of pulsed antibiotic protocols with doxycycline. It’s not out of the question, but decimating your microbiome is counterproductive.
Online retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
With that being said, let’s discuss the wonderful thing we call CBD oil. CBD oil is made from the specific hemp strain that is bred for fiber, topicals, nutritional benefits, and more. It is made from high-CBD, low-THC hemp. CBD oil is extracted using the whole plant or aerial parts. Aerial parts of the plant are parts which are completely exposed to air. Since hemp contains only trace amounts of THC, CBD oil products are non-psychoactive.
Though unflavored and priced higher than competitors, Green Roads CBD oils are made by a trusted manufacturer and use organically grown hemp. Following the CO2 supercritical fluid extraction process, board-certified pharmacists formulate the tincture by hand. Green Roads only sells CBD isolates, so if you’re looking for broad-spectrum products look to some of our other recommendations.

I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
Anyone who tells you anything definitive about what CBD — or THC, for that matter — does to your body is lying. Nobody knows. The legitimate research out there is extremely limited, and the slow drip of legalization — medical use, then personal use, federally illegal but permitted by certain states and cities — has made it incredibly hard for researchers to do their jobs.
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
Almost overnight, CBD oils have become an interesting combination of popular holistic medicine, miracle cure, and a natural answer to the synthetic drugs dominating modern medicine. With CBD, patients receive the promise of being in control of their own ailments, and no longer feeling at the mercy of their treating physicians. This has turned out to be a particularly powerful message. Many patients use CBD oils freely for ailments both confirmed and self-diagnosed, and the rapid innovations with CBD products have actually been quite impressive. But while new CBD products keep entering the market virtually unchecked, effective regulatory control of these products has stayed far behind. As a result, unknown risks about long-term effects remain unaddressed, especially in vulnerable groups such as children, the elderly, and the chronically or terminally ill. It should be noted that this discussion goes well beyond CBD only, as new products containing additional cannabinoids like CBG, THCV, and acidic cannabinoids are following closely behind. We know even less about these compounds than about CBD, and very limited human safety data are available.
While we hope you’ll give our CBD latte a try, making CBD coffee doesn’t have to be complicated. Adding a little flavorful drop of CBD oil to your morning coffee is a simple step to start your day out healthier and happier! Of course, there’s no reason you can’t add it to your afternoon pick-me-up cup, too. Either way, it’s a great step in the right direction.
This has been the year medical cannabis hit the mainstream. The government has announced that it is relaxing laws on when cannabis medicines can be prescribed by doctors, following high-profile cases such as that of Billy Caldwell, the 13-year-old boy hospitalised by his epileptic seizures after he was denied legal access to the cannabis oil that helps control them. Meanwhile a new generation of cannabis medicines has shown great promise (both anecdotally and in early clinical trials) in treating a range of ills from anxiety, psychosis and epilepsy to pain, inflammation and acne. And you don’t have to get stoned to reap the health benefits.

In just a few years, cannabidiol (CBD) has become immensely popular around the world. After initially being discovered as an effective self-medication for Dravet syndrome in children, CBD is now sold and used to treat a wide range of medical conditions and lifestyle diseases. The cannabinoid CBD, a non-psychoactive isomer of the more infamous tetrahydrocannabinol (THC), is available in a growing number of administration modes, but the most commonly known is CBD oil. There are currently dozens, if not hundreds, of producers and sellers of CBD oils active in the market, and their number is increasing rapidly. Those involved vary from individuals who prepare oils on a small scale for family and (Facebook) friends to compounding pharmacies, pharmaceutical companies, and licensed cannabis producers. Despite the growing availability of CBD, many uncertainties remain about the legality, quality, and safety of this new “miracle cure.” As a result, CBD is under scrutiny on many levels, ranging from national health organizations and agricultural lobbyists to the WHO and FDA. The central question is whether CBD is simply a food supplement, an investigational new medicine, or even a narcotic. This overview paper looks into the known risks and issues related to the composition of CBD products, and makes recommendations for better regulatory control based on accurate labeling and more scientifically supported health claims. The intention of this paper is to create a better understanding of the benefits versus the risks of the current way CBD products are produced, used, and advertised.


In the European Union (EU), the cultivation of certain cannabis varieties is granted provided they are registered in the EU’s Common Catalogue of Varieties of Agricultural Plant Species [27] and the THC content does not exceed 0.2% of the dried flowers of the plant [28]. In Canada, hemp is allowed to contain 0.3% THC [29], while Switzerland allows up to 1% THC [30]. In most countries, viable seeds for planting may be purchased from certified seed companies only, in order to make sure that the correct hemp variety is indeed being cultivated. Additionally, hemp may typically only be grown in agricultural fields outdoors, while indoor cultivation is usually forbidden. In some countries (e.g., The Netherlands), growing hemp is allowed only with the intent to produce fibers or seeds. As a result, the act of harvesting fiber cannabis for its CBD is a violation of narcotics laws [31]. New cannabis varieties (for example developed to yield a higher content of CBD) are not (yet) registered as approved hemp varieties, and therefore cannot be freely cultivated, while the official registration process takes several years to complete.
Clancy says his dose estimates are based on a book called CBD: A Patient’s Guide to Medicinal Cannabis: Healing Without the High. The co-author of that book is Leonard Leinow, the founder of Synergy Wellness, which calls itself a “hand crafted artisanal CBD cannabis collective.” He is not a doctor or a scientist, but he is a sculptor of erotic bronze pieces, like a yin-yang symbol made up of two interlocking penises.

By popular demand, we have also begun to carry several, high quality CBD pet products as well. For general purpose applications, we carry several, tasty tincture and oral spray options that are highly effective. Likewise, Pharma CBD capsules provide CBD purity via capsular ingestion. In addition, we have partnered with Therabis, the quality CBD maker of “Stop the Itch” and “Calm and Quiet”, the pet lovers’ ultimate go-to’s. Find these products by browsing our exclusive online inventory.
CBD may help reduces REM behavior disorder in people with Parkinson’s disease. REM behavior disorder is a condition that causes people to act out physically during dreaming and REM sleep. Typically, during REM, the body is largely paralyzed, a state known as REM atonia. This immobilization keeps sleepers from reacting physically to their dreams. In REM behavior disorder, this paralysis doesn’t occur, leaving people free to move—which can lead to disruptive sleep and to injuring themselves or their sleeping partners. Cannabis may also work to reduce pain and improve sleep quality in people with Parkinson’s disease.
Still, CBD is already commonly used to relieve some symptoms of anxiety, including insomnia, and there have been some studies that show it to be effective in those cases. Other studies have shown that CBD could have anti-inflammatory properties, and many CBD products are marketed for relieving chronic pain, such as arthritis. And multiple studies have found CBD to be an effective treatment for seizures, and there are various CBD products that are used by patients with epilepsy. However, major health agencies like the U.S. Food and Drug Administration, National Institutes of Health and the World Health Organization have all stated in recent years that additional CBD testing and research is necessary.
CBD oil is most readily available as a tincture. This can be taken by applying a few drops under your tongue, holding in your mouth for a few moments so it can be absorbed, before swallowing. It can also be added to water or smoothies. A spray form is available (simply spritz under your tongue), as are capsules, creams that can be applied topically, and e-liquid for vape pens.

Hi, I have had spondylolisthesis since age 11 which left me with extreme nerve pain...restless leg syndrome. Had 3 spinal ops and also had hip surgery 2 years ago. have asthma and hypothyroidism. I can deal with everything else but this nerve pain is insane. Used Gabapentin for 9 years and now its not in the market in Nairobi, Kenya where I live. Am on Lyrica, which is not working. I started Cbd oil in August but now found my body has become immune to the effects of pain releif I was getting. Can anyone suggest what strength oil/cbd supplement I should aim for? Currently am making flapjacks with weed, have one every night but this makes me high which I dont want. I still wake up in pain at night, please help.
Hey, I’m a simple guy; I like my ice cream cold, my t-shirts tight, and my coffee alarmingly strong. With the relaxation of marijuana laws in some U.S. states, it seems an array of industries have started cashing in on the great green prize by offering CBD-infused products—which is legal almost everywhere. Moisturizer, sugar, lube, and—of course—coffee.  Not to be dramatic, but CBD coffee is a ridiculous trend that’s turning grown adults into giant throbbing knobs. Here’s why.
^ Hayakawa K, Mishima K, Hazekawa M, Sano K, Irie K, Orito K, Egawa T, Kitamura Y, Uchida N, Nishimura R, Egashira N, Iwasaki K, Fujiwara M (January 2008). "Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism". Brain Research. 1188: 157–64. doi:10.1016/j.brainres.2007.09.090. PMID 18021759.
A 2017 article published by the National Academies of Sciences, Engineering and Medicine conducted a study in which the results concluded, “In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.” This statement is quite a massive development for the increasing of tolerance towards CBD and CBD based products.
Given the degree to which marijuana and cannabinoid derivative use has been stigmatized in the past, their Schedule I classification as illegal substances, and lack of FDA approval, valid medical research on the effects of CBD isn’t as plentiful as it should be. Much of the anecdotal evidence, however, suggests that CBD’s neuro- protective, analgesic, and anti-inflammatory effects with regard to topical applications are promising.2
Cannabinoids are a class of compounds that interact with receptors throughout your body. CBD is just one of dozens of cannabinoids found in cannabis, including tetrahydrocannabinol (THC), which is the one responsible for marijuana’s famous high. Medical cannabis is technically any cannabis product used for medicinal purposes, and these can contain THC or CBD or both, said Nick Jikomes, a neuroscientist at Leafly, a website that provides information about legal cannabis. “A common mistake people make is to think that CBD is ‘the medical cannabinoid’ and THC is ‘the recreational cannabinoid.’” That’s inaccurate, he said, because THC is a potent anti-inflammatory and can be helpful for pain.
Topicals are cannabis-infused lotions, balms, and oils that are absorbed through the skin for localized relief of pain, soreness, and inflammation. Because they’re non-intoxicating, topicals are often chosen by patients who want the therapeutic benefits of marijuana without the cerebral euphoria associated with other delivery methods. Other transdermal innovations are fast arriving in the cannabis market, including long-lasting patches and tingly lubricants for patients and recreational consumers alike.
Right now, there’s a good chance that you don’t really know what you’re getting from any source. Testing and labeling rules vary by state, but many states that allow legal cannabis also require some kind of testing to verify that the THC and CBD levels listed on the label are accurate. However, this testing is controversial, and results can vary widely between labs, Jikomes said. A study published in March found measurable variations in test results, with some labs consistently reporting higher or lower levels of cannabinoids than others. There are no guarantees that the label accurately reflects what’s in the product. For a 2015 study published in JAMA, researchers tested 75 products purchased in San Francisco, Los Angeles and Seattle and found that only 17 percent were accurately labeled. More than half of the products contained significantly lower levels of cannabinoids than the label promised, and some of them contained only negligible amounts of the compounds. “We need to come up with ways to confidently verify the composition of cannabis products and make this information available to consumers,” Jikomes said.
A few weeks ago, in a bike shop–slash–coffee shop in Williamsburg, Brooklyn, I saw a little sign for a new product on offer: a CBD lavender latte. I didn’t get one, in part because it was 80 degrees outside, and also because my experiences with CBD are somewhat mixed. I have some gummy fruit candy that puts me straight to sleep, and I found using an oil dropper on my tongue too disgusting-tasting to be worth whatever marginal benefits it may have given me. But I knew other anxious people have had good experiences with CBD, and I like coffee, so I was interested — though I did wonder if coffee (a stimulant) and CBD (a cannabinoid thought to have relaxing properties) might just cancel each other out.
Researchers like Blessing are legitimately excited about CBD. It shows real promise in treating previously intractable disorders like schizophrenia, and without the destructive side effects of existing drugs. Still, that doesn’t mean CBD is harmless. Research on drug interactions with CBD is in its infancy, but what is known within the medical community is that CBD can cause serious problems for people taking certain classes of drugs, namely SSRIs (a group of antidepressants including Zoloft and Prozac) and opioids.

Leafly is the world’s largest cannabis information resource, empowering people in legal cannabis markets to learn about the right products for their lifestyle and wellness needs. Our team of cannabis professionals collectively share years of experience in all corners of the market, from growing and retail, to science and medicine, to data and technology.
Hemp Extract Oil* and Hemp Oil are from a different Cannabis plant called Cannabis Sativa.  Hemp Extract is made from the entire plant including leaf, seed and stem.  Most oils on the market selling as C B D oil are 97% or more Hemp Seed Oil, mct oil or vegetable glycerine and 3% Hemp Extract. This does not contain THC and is legal in all 50 states.
×