West maintains that there are plenty of reasons someone would explore this combo. And she should know: She manufactures her own brand of CBD coffee. “I’d bet that at this point, many adults have heard about CBD in the news or have come across ads for CBD products, but they might not know exactly what it is or how to try it,” she says. “Coffee, on the other hand, is a part of so many people’s everyday lives. So coffee is actually a perfect, natural way for people to explore the potential benefits of CBD.”
I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.
Various studies done on CBD oils and other cannabis products around the world have come to similar conclusions about incorrect label information [24, 53, 54] and the presence of contaminants [54-57]. In the absence of a clear legal status for CBD, or agreement on common safety and quality standards, it may not be surprising that current CBD products leave something to be desired. The time has come for regulators to give CBD the attention it deserves in order to ensure that affordable, safe, and reliable CBD products are available to those who depend on them.
Recently, an interesting study performed in the Netherlands highlighted multiple issues that may be extrapolated to CBD products elsewhere . In this study, 46 different cannabis oil samples were collected directly from patients and analyzed for cannabinoid content. The obtained samples were home-made (n = 29) or purchased from a (web) store (n = 17). For 21 of the 46 products (46% of all samples), label information was available on CBD/THC content, so that the claimed content could be compared to the analyzed content as determined in the study. Results are shown in Table 1. In many cases the analyzed cannabinoid content strongly differed from the claimed content on the label, while in 7 samples no cannabinoids (CBD or THC) were found at all. Such deviations were found in home-made as well as commercially obtained products.
CBD oil extracted from hemp — no matter how it’s consumed — works with the body’s ECS system to replenish cannabinoids and regulate homeostasis. The substance is also anti-anxiolytic, meaning it reduces feelings of anxiety — a common source of sleep problems in adults. For these reasons, hemp-based CBD oil can be highly beneficial for people with insomnia whether they struggle with sleep onset (falling asleep) or sleep maintenance (staying asleep). In addition to insomnia, CBD oil may lead to improvements for the following sleep disorders:
CBD is derived by growing cannabis, drying it out, pulverizing it, and then, often, using a rotary evaporator filled with an ethanol solvent to extract the CBD. (There are some other methods, but the ethanol one is common.) It’s a pretty old and fairly low-tech technique, but it’s effective. What you end up with is, hopefully, about 99 percent pure CBD in the form of white powder, which is called CBD isolate. (Some CBD is billed as “full spectrum,” which means it contains other things from the cannabis plant, like a bunch of other cannabinoids, but there’s no formal definition for full spectrum.)
Cannabidiol is currently a class B1 controlled drug in New Zealand under the Misuse of Drugs Act. It is also a prescription medicine under the Medicines Act. In 2017 the rules were changed so that anyone wanting to use it could go to the Health Ministry for approval. Prior to this, the only way to obtain a prescription was to seek the personal approval of the Minister of Health.
By definition, ointments must be infused with medicine, in this case CBD, and are of a semi-solid almost mucus-like consistency. Creams typically involve water or some type of aqueous substance as their base, while salves utilize only oils or waxes for their foundation. Ointments tend to contain a combination of oils, water and alcohols within their formulation.
CBD is showing real promise as a compound that can contribute to protecting the brain, thanks to its anti-oxidant and anti-inflammatory abilities. Scientists are investigating its role in neurogenesis and its ability to help the brain heal from injury, and as a treatment for neurodegenerative disease. Research suggests that CBD may help to reduce brain damage from stroke or other neurological injury. And CBD is increasingly looked to as a possible therapy for several neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and multiple sclerosis.
I was sceptical, but decided to try the cream for my chronic hip pain! It was amazing! Within 15 minutes, my pain is almost gone! I am a nurse and am on my feet ALOT! I am so excited about this product that I share my experience with my patients and friends that have pain issues! It feels so good to be using a natural product that has no side effects and that actually works!! Thank you so much!
Medical reviews published in 2017 and 2018 incorporating numerous clinical trials concluded that cannabidiol is an effective treatment for certain types of childhood epilepsy. An orally administered cannabidiol solution (brand name Epidiolex) was approved by the US Food and Drug Administration in June 2018 as a treatment for two rare forms of childhood epilepsy, Lennox-Gastaut syndrome and Dravet syndrome.
Hemp-derived CBD definitely had an effect on me. At Caffeine Underground, I ordered a CBD oat milk latte—smooth and delicious with no trace of CBD flavor—and toast made with CBD-infused jam. After two hours plugging away on my laptop with full concentration, I was still so completely blissed out, the walk back to the train in 30-degree weather felt like it took no time at all.
Cannabidiol has been found to act as an antagonist of GPR55, a G protein-coupled receptor and putative cannabinoid receptor that is expressed in the caudate nucleus and putamen in the brain. It has also been found to act as an inverse agonist of GPR3, GPR6, and GPR12. Although currently classified as orphan receptors, these receptors are most closely related phylogenetically to the cannabinoid receptors. In addition to orphan receptors, CBD has been shown to act as a serotonin 5-HT1A receptor partial agonist, and this action may be involved in its antidepressant, anxiolytic, and neuroprotective effects. It is an allosteric modulator of the μ- and δ-opioid receptors as well. The pharmacological effects of CBD have additionally been attributed to PPARγ agonism and intracellular calcium release.
Thapa, D., Toguri, J. T., Szczesniak, A. M., & Kelly, A. E. M. (2017, April 1). The non-psychoactive phytocannabinoid, cannabidiol (CBD), and the synthetic derivatives, HU308 and CBD-DMH, reduces hyperalgesia and inflammation in a mouse model of corneal injury [Abstract]. FASEB Journal. Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.811.7
Beyond pain management, CBD products have a multitude of other uses, both medical conditions and just the daily occurrences of human beings. Millions, if not billions of consumers have already described in detail their immense success with cannabidiol. We hope you found this article to not only be entertaining, but also educational, informative and revealing.
Topicals are applied right to trouble areas so that the CBD oil can work directly where it’s needed most. Ingesting CBD products orally causes CBD and other compounds to enter the bloodstream, which elicits full-body effects and takes up to 2 hours or more before those effects are experienced. With CBD topicals, the healing compound and other hemp-derived nutrients are almost immediately absorbed directly through your skin, allowing them to target the affected area for quicker and more focused effects.
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner. In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity. A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.
Ingredients: Aloe Barbadensis (Aloe Vera) Leaf Juice*, Purified Water, Carthamus Tinctorius (Safflower) Oleosomes, Butyrospermum Parkii (Shae) Butter*, Cocos Nucifera (Coconut) Oil*, Vegetable Glycerin**, Cetearyl Olivate, Sorbitan Olivate**, Mangifera Indica (Mango) Seed Butter*, Lactobacillus Ferment (from Cabbage)**, Lactobacillus, Cocos Nucifera (Coconut) Fruit Extract**, CW Hemp Oil CO2 Extract, Mentha Piperita (Peppermint) Leaf Extract, Arnica Montana Flower Extract, Curcuma Longa (Turmeric) Root Extract, Salix Alba (Willow) Bark Extract, Cimicifuga Racemosa (Black Cohash) Root Extract, Prunus Armeniaca (Apricot) Kernel Oil*, Simmondsia Chinensis (Jojoba) Seed Oil*, Glyceryl Stearate (Palm Oil Derived), Xanthan Gum, Panthenol (Vitamin B5), Tocopheryl Acetate (Vitamin E), Cyamopsis Tetragonolobus (Guar) Gum*, Sodium Benzoate, and Potassium Sorbate.