“CBD is the most promising drug that has come out for neuropsychiatric diseases in the last 50 years,” said Dr. Esther Blessing, an assistant professor at New York University School of Medicine, who is coordinating a study of CBD as a treatment for post-traumatic stress disorder and alcohol use disorder. “The reason it is so promising is that it has a unique combination of safety and effectiveness across of very broad range of conditions.”
Ingesting — think CBD lattes, edibles, or just a drop of oil on the tongue — is likely much less effective than inhaling, says Blessing. When CBD-containing oil is ingested, it wants to join the other fat in your body; most of the CBD taken this way will just stay in that fat, inert and never getting to the brain. When inhaled, CBD bypasses the digestive system, which wants to store fat.

I tried the CBD oil that comes from hemp cause that’s all that’s legal where I live and was really hoping it would help with my back pain but it does absolutely nothing. Might as well have bought a bottle of vegetable oil & saved $150. I think it’s the THC that’s in medical marijuana that offers true pain relief, looking forward to it being legal across the country not just in 30 states.


CBD oil derived from whole-plant marijuana has seen promising results for numerous medical treatments, including treating children with epilepsy. (In 2013, CNN’s Dr. Sanjay Gupta introduced the world to a child who after using CBD oil went from having 300 seizures a month to only two.) On April 19, the AP reported that an FDA panel is reviewing a a pharmaceutical-grade CBD oil made from whole-plant marijuana called Epidiolex, a possible treatment for rare forms of pediatric epilepsy. If approved, it would be the first marijuana-made medication sold on the U.S. market. A day later, on the marijuana community’s “high holiday,” April 20, New York Senator Chuck Schumer introduced legislation to decriminalize marijuana on the federal level. Forecasters are predicting that legal cannabis in the U.S. will be outselling soda by 2030.
We have been using cannabis oil with a 1:1 CBD/THC ratio from “AnnCannMed” in treating my husband with pancreatic cancer with a lot of improvement since 4 weeks and the product is working in a miraculous way beyond our expectations. The medication is working with super proof. We recommend you visit AnnCannMed for your health prescriptions and medical purchases and feel support talking to licensed physicians
It’s important that you are applying the CBD topical to areas of the skin that are unaffected by other skin-care products. Making sure that you are applying your topicals to clean, product-free skin ensures that your skin is effectively absorbing the oil in its entirety. Mixing CBD oil with other products will only dilute the effects and reduce its effectiveness.
I have severe neuropathy in both feet and legs. I just got the CBD oil and I am interested in learning if anyone out there has had any success with this. I know each case and pain levels are different. Just would like to see some positive remarks from people who suffer with it. I am not looking for a cure just need an update on someone who took and it helped. I already know there is no cure. I need help with the pain. Thank you.
Out of all the CBD products I’ve tested and used in the past few weeks, this thick green lemon-vanilla scented salve is my favorite. I massage it onto my sore red knuckles after boxing practice, and if it weren’t so expensive, I would encase my entire body in it. The cannabis sativa seed oil in this salve has antioxidant properties so that your skin can repair itself from the inside out, while the thick balm-like formula protects your skin from environmental aggressors. I would not recommend rubbing this onto your face because it’s so thick, but do whatever you want on the rest of your body—and if your feet are in need of some serious TLC in time for summer sandals weather, consider rubbing this onto your cracked heels and putting on a pair of soft socks before bed. The next morning, you’ll have baby’s feet again.
Unfortunately, due to strict FDA laws, I am not legally able to say that CBD will help with your husbands specific condition, however I can direct you to some literature to help you better understand what CBD may offer. I have attached links below. As far as strength and dosage goes, tinctures and concentrates are absorbed the fastest since it goes directly into your blood stream; the dosage on these can be measured and controlled. Capsules take a little longer to enter your body since it goes through your digestive tract, these are also measured and controlled. I would recommend reading through our page on dosing as well to get a better understanding.https://cbdoilreview.org/cbd-cannabidiol/https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/I hope these help :)
…..i have an aggressive form of heart disease (atherosclerosis) and my on-line research into medical marijuana has uncovered that there are 2 main forms of canabidiol, CBD 1 and CBD 2. Current research is indicating that CBD 1 promotes the growth of arterial plaque while CBD 2 inhibits this growth. Thus, I would like to use a strain that is high in THC and high in CBD 2 with no CBD 1. Is there anything out there with this combination (THC/CBD2) ?? Thanks !!

Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps


Recreational marijuana is not legal in New York state. What the coffee shop is selling is CBD-infused lattes; CBD, which stands for cannabidiol, is a non-psychoactive compound found in the cannabis plant. Out of curiosity, I bought one. It cost $9 and tasted like a latte with that hint of marijuana herbiness you get from a weed cookie. Google research informed me I would not get high but would be calmer, less anxious, maybe a little sleepy. I have no idea if I felt anything at all. Mostly, I felt like I just spent $9 on coffee.
Hi I've had rsd over 25 years now and in stage 3 I take cbd I'mor nong 6 weeks now and it's helped tons w my depression,sleep,constipation as well as energy. I take 2 drops under tounge every morning and Rick spson oil 3 xs day.It's bern beyond life changing for me look into the rs oil w the cbd. It works.. I still take 1 opiad a day have taken 2 a day only 3 times in almost 2 months when I was in bad flare ..
If you want a daily CBD therapy that actually tastes like a “proper” cup of java, on the other hand, you really do need to set yourself up with a well-made, properly infused CBD roast. The best cannabis-incorporating master roasters (which we’ll talk about below) have spent years devising and perfecting specific roasting processes that allow for efficient CBD infusion, without having to sacrifice any traditional coffee taste.
“Placebo response always needs to be taken into account for any treatment being studied,” says Baron. “Placebo response is actually quite high in many pharmaceutical trials, for example. In fact, there are many treatment trials for various medications and other treatments where benefit responses to placebo are actually higher than the treatment itself being studied.”
Oils are hot in the beauty world. As a beauty editor, I’ve slathered everything short of butter onto my face: argan, coconut, rosehip, sandalwood, chia, neroli, calendula, mandarin, macadamia, rice bran, seabuckthorn, patchouli, grapefruit seed, sesame seed, soybean, sweet almond, pomegranate seed, lemon myrtle, sunflower seed—even extra virgin olive oil from my pantry when I was desperate. I’ve washed my face with oil-based cleansers, and dabbed expensive mixtures being sold as “face oils” onto my skin in hopes of achieving that Instagram-ready glow. Contrary to popular belief, the right oil is actually good for your face and won’t clog your pores. Your skin needs a reasonable amount of oil to do its business; as a matter of fact, if you scrub away all your natural face oil (as I was prone to do with rubbing alcohol as a frustrated and misguided pizza-faced teen), you may actually be prone to more breakouts as your skin tries to make up for the imbalance. As cannabis meets up with the mainstream beauty world, cannabidiol (CBD) oil may be the next big thing.
However (and this is very important), as has typically been the case with legal marijuana, the federal government mostly looks the other way while individual states decide how to treat CBD. As such, most states allow CBD products in some form, usually for medical purposes. The 30 states that have legalized medical marijuana include CBD products in that protection, while a number of other states have specific CBD laws that allow for those products in some form, so long as they also contain no more than a miniscule amount of THC. Only four states consider all cannabis-derived products, including CBD, to be illegal: Idaho, South Dakota, Nebraska and Kansas.
So far, by far the best medicinal relief I have found for my symptoms is a particular strain of cannabis flower called Harlequin — it contains an almost 3:1 ratio of CBD:THC, which is extremely rare and unique in the cannabis world. There are multiple studies you can find online showing the SYNERGISTIC effects of CBD combined with THC. When they are used together, they are much more medicinally effective than either one is on their own. Most cannabis strains today have zero CBD because growers realized everyone just loves their THC, but the Harlequin strain is a god send.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia. 

“Research shows that CBD content decreases when it is exposed to heat. It’s likely that the reduction in efficacy is due to the lower content. For instance, studies show that 71 degrees F can accelerate the degradation of CBD in a solution, resulting in less CBD. Potentially adding CBD to hot coffee may degrade it and reduce the amount of CBD available for absorption."
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.

Everybody has different medical needs, because of this Medix CBD hemp oil tinctures are available in different dosages ranging from 100mg – 4,500mg per bottle. The reason for such a large difference in CBD concentrations between the lowest strength bottle and the highest strength bottle is because we offer a vast and wide selection of CBD hemp oil tinctures to meet the needs of people with different medical goals.


Disclaimer: This product is not for use by or sale to persons under the age of 18. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.

Larilyn, Great question. Most CBD oils are hemp-derived, which, by definition, means they generally contain 0.3 percent THC. That being said, there is no way to guarantee that a person will pass a UA screening due to variables within that persons composition & other influences. Some people will turn to a isolate version zero percent THC of CBD for this reason but in doing so will not reap the benefits of full spectrum. I prefer the option of Enterouge oil for these candidates.
Research suggests that CBD may exert some of its pharmacological action through its inhibition of fatty acid amide hydrolase (FAAH), which may in turn increase the levels of endocannabinoids, such as anandamide, produced by the body.[8] It has also been speculated that some of the metabolites of CBD have pharmacological effects that contribute to the biological activity of CBD.[42]
Everyone wants a piece of CBD, and nobody is watching. Remember: There’s no regulation by the FDA or anyone else. An investigation by Natural Products Insider, a trade publication for the supplement industry, revealed that CBD producers are, at best, claiming to follow “good manufacturing practices” without any official oversight. It’s illegal to sell something that isn’t what its packaging claims it is — that falls under the purview of the Federal Trade Commission — but nobody is doing onsite testing.
In fact, the majority of them report that CBD actually seems to work phenomenally well with the caffeine – they claim that it reduces cases of the “jitters” (which makes sense considering that CBD is a well-known anti-spasmodic), and also that it works wonders in terms of elevating mood, increasing mental acuity, and promoting general productivity.
CBD products have become increasingly popular in recent years, as more and more producers market CBD as the new "it" drug for the health and wellness set — one that has been touted as a pain reliever and a treatment for anxiety, among other potential applications. Last year, consumer sales of CBD products topped $350 million in the United states, more than triple the amount sold in 2014, and various estimates predict the market could reach $2 billion within the next two to four years.

THC, an intoxicating and illegal substance, is responsible for causing marijuana users to get “high.” Unlike THC, CBD is non-psychoactive because it does not act on the same pathways as THC. Thus, it is impossible to get “high” by smoking or ingesting CBD or CBD oil extracted from industrial hemp plants, as they only have minuscule traces of THC (<0.3%).
This is a whole new idea to me and I can use any help you can offer. I suffer from post stroke pain in my thigh which sounds similar to the pain diabetics feel in their feet (sort of electric shocks shooting through my skin). I’ve had this 24/7 for about 5 years now. The 600 mg Gabapentin 3 times a day is no longer helping. A friend just suggested marijuana topicals which I had never heard of! Any recommendations?

I have numerous areas of severe pain in my back,neck, legs, and feet, + have suffered for 25 years from Fibro. I was so impressed with this cream!! It takes so little - not even a full squeeze of cream to cover my entire foot, or my spine, neck, and lower back. The cream does NOT need to be massaged into the painful area - just applied to the surface. Less than five minutes later, whammo! Literally NO PAIN, and it lasted for most of the day. I'm talking hours upon hours of relief!
Cannabidiol is currently a class B1 controlled drug in New Zealand under the Misuse of Drugs Act. It is also a prescription medicine under the Medicines Act. In 2017 the rules were changed so that anyone wanting to use it could go to the Health Ministry for approval. Prior to this, the only way to obtain a prescription was to seek the personal approval of the Minister of Health.
If you want a daily CBD therapy that actually tastes like a “proper” cup of java, on the other hand, you really do need to set yourself up with a well-made, properly infused CBD roast. The best cannabis-incorporating master roasters (which we’ll talk about below) have spent years devising and perfecting specific roasting processes that allow for efficient CBD infusion, without having to sacrifice any traditional coffee taste.
The discussion on the legal status of CBD revolves mainly around the question: is it a medicine or a natural food supplement? The main difference is that medicinal drugs are considered unsafe until proven safe, whereas food supplements are considered safe until proven otherwise. As a result, the central question becomes whether or not CBD is safe for consumers (children, elderly, patients) in large and unregulated quantities. Although there is only limited knowledge about the long-term effects of chronic use, or about drug-drug interactions between CBD and other medications [36], human studies have indicated that CBD is very well tolerated even up to a daily dose of 1,500 mg [37]. Indeed, a recent World Health Organization (WHO) review concluded that “to date, there is no evidence of recreational use of CBD or any public health-related problems associated with the use of pure CBD” [38]. However, the risks to be assessed about CBD products may not have much to do with the pure compound CBD itself, but more with the unknown composition and quality of the products offered. In particular, we should be looking into the presence of contaminants in these concentrated extracts, and into incorrect or even misleading labels for the cannabinoid content of products.
^ Hayakawa K, Mishima K, Nozako M, Ogata A, Hazekawa M, Liu AX, Fujioka M, Abe K, Hasebe N, Egashira N, Iwasaki K, Fujiwara M (March 2007). "Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance". Neuropharmacology. 52 (4): 1079–87. doi:10.1016/j.neuropharm.2006.11.005. PMID 17320118.
Various strains of "medical marijuana" are found to have a significant variation in the ratios of CBD-to-THC, and are known to contain other non-psychotropic cannabinoids.[61] Any psychoactive marijuana, regardless of its CBD content, is derived from the flower (or bud) of the genus Cannabis. Non-psychoactive hemp (also commonly-termed industrial hemp), regardless of its CBD content, is any part of the cannabis plant, whether growing or not, containing a ∆-9 tetrahydrocannabinol concentration of no more than three-tenths of one percent (0.3%) on a dry weight basis.[62] Certain standards are required for legal growing, cultivating and producing the hemp plant. The Colorado Industrial Hemp Program registers growers of industrial hemp and samples crops to verify that the THC concentration does not exceed 0.3% on a dry weight basis.[62]
Right now, there’s a good chance that you don’t really know what you’re getting from any source. Testing and labeling rules vary by state, but many states that allow legal cannabis also require some kind of testing to verify that the THC and CBD levels listed on the label are accurate. However, this testing is controversial, and results can vary widely between labs, Jikomes said. A study published in March found measurable variations in test results, with some labs consistently reporting higher or lower levels of cannabinoids than others. There are no guarantees that the label accurately reflects what’s in the product. For a 2015 study published in JAMA, researchers tested 75 products purchased in San Francisco, Los Angeles and Seattle and found that only 17 percent were accurately labeled. More than half of the products contained significantly lower levels of cannabinoids than the label promised, and some of them contained only negligible amounts of the compounds. “We need to come up with ways to confidently verify the composition of cannabis products and make this information available to consumers,” Jikomes said.
Different topicals have different benefits to offer depending on the way they are processed and the ingredients that are used, so experiment with various transdermal products to see what works for you. Medical marijuana states are seeing more and more options for topical remedies as time goes on, and for sufferers of pain and inflammation, it’s worth exploring. You’d be surprised the difference that one special ingredient makes.
A study analysis in Journal of Pain Research confirms that topical use of certain cannabinoid topicals can reduce pain in animals with inflammation or neuropathic pain. And science has found topical creams with THC and CBD help relieve pain for conditions like multiple sclerosis. But for the vast majority of chronic pain—and most certainly for acute pain like post-workout—the scientific jury is 100 percent still out. "There's a little bit of data in support of CBD for pain relief, but to go from animal to human is a giant leap," Sexton says.
If you read the ingredient list, often everything in the jar is straight from mother earth. As long as that's indeed the case with the cream you have your eye on, the formula is immensely safe, chemically, says Gregory Gerdeman, Ph.D., neurophysiologist who researches cannabinoid biology and pharmacology at Eckerd College in Saint Petersburg, FL.. And since they're formulated to be topical—absorbing into the top layer of skin—and not transdermal—which would pass through the skin and into your bloodstream—there's no risk of getting high, Gerdeman explains. (P.S. Here's How Marijuana Affects Athletic Performance.)
It is your full responsibility to verify the customs, duties charges, and procedures in your country prior to placing your order. If customs fees and charges are refused at the time of delivery, your order will be returned and you will not receive a refund for shipment costs. IBC is also not responsible for goods that are seized by foreign or domestic customs agencies.
Thanks for your interest in our products. Unfortunately due to strict FDA regulations I am unable to make claims on our products based on your specific needs, I can though share our top selling products in each category. Please view the links below:http://cbdoilreview.org/product/elixinol-cbd-oil-extract-x-pen-1000mg/http://cbdoilreview.org/product/endoca-hemp-oil-drops-1500mg/http://cbdoilreview.org/product/elixinol-hemp-oil-drops-regular-300mg/http://cbdoilreview.org/product/elixinol-cbd-hemp-oil-capsules-900mg/https://cbdoilreview.org/product/vape-bright-thrive-cbd-vape-cartridge-200mg/As far as dosage goes, I would recommend reading through our page on dosing. I have attached that link below. https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/Hopefully these help.
Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn

As a healthcare professional I have realized over the years that most physicians and our healthcare system in general are all set up to focus almost entirely on symptoms and the disease state as a problem to treat, not prevent unfortunately. The training that most physicians receive is almost completely pharmacologicaly focused and consequently they treat patients almost as if they are a car to be fixed rather than as a living breathing being.


Ingesting — think CBD lattes, edibles, or just a drop of oil on the tongue — is likely much less effective than inhaling, says Blessing. When CBD-containing oil is ingested, it wants to join the other fat in your body; most of the CBD taken this way will just stay in that fat, inert and never getting to the brain. When inhaled, CBD bypasses the digestive system, which wants to store fat.
Locsta....I share your pain of degenerative and bulging disk disease, along with fibromyalgia, chronic fatigue and arthritis. Absolutely no energy and chronic pain all day, every day. I'm curious as to what type and brand of the CBD oil you are taking and for how long have you been using it? I've been researching CBD oil for months and am quite confused!
Canabidol™ CBD cannabis oil (CBD Oli) is derived from EU approved, UK & US legal, industrial hemp (Cannabis Sativa L.) The active ingredient is Cannabidiol as our products are THC free, meaning that they are non psychoactive so will not get you high. CBD Oil (Cannabidiol) is not scheduled and is found in all hemp products which makes it legal in both the UK and US. Manufactured in England to the highest standards Canabidol™ is now sent out from our United Kingdom distribution centre.  You can also purchase our range of CBD oil products direct from one of our many stores across the UK.
This mint-green bath bomb, made by Los Angeles-based De La Beuh, combines the invigorating aromatherapy of peppermint oil with the pain relief benefits of CBD. I sat in the bath with this bath bomb soak for an hour—until the water ran cold—when I had both cramps and lower back aches, and while it doesn’t beat ingesting a painkiller, it did help soothe my pains so that I fell asleep as soon as I hit the pillow. De La Beuh sells bath bombs in many varieties—including a glittery Kaleidoscope version that will turn your bath into “unicorn” colors—so your preference just depends on your preferred aroma.
“If you’re taking Prozac or some other medication, you really need to think carefully about what you’re doing, because it can harm you, and you should talk to your doctor about it,” says Blessing. Blessing does note that while the drug interactions are potentially very serious, the doses in consumer CBD products are so low that the risk is likely minimal. Regardless, the fact that CBD has drug interactions should indicate that it is, at least sometimes, in some doses, actually doing something.
Carson, too, speculates that CBD might be able to reduce some of the jitteriness associated with caffeine intake, thus complementing it rather than canceling it out. “I can’t say I’ve spent much time in New York, but when I was thinking about talking to you, I got this vision in my head of a stereotypical taxi driver drinking a huge cup of coffee and being really alert but irritable,” he says. “And now if you add in a little CBD, they’re really alert but maybe a little more calm, and not as apt to honk the horn. I think that’s a potential area where there could be something good that comes from adding CBD to the coffee.”

I have read that taking CBD oil may help in the reduction of the size of tumors (specifically brain tumors). I’ve been taking Hemp oil instead, as that’s what came up when I did a search for CBD oil on a popular website. (My first bottle was not flavored and tasted absolutely horrible. Next one was mint-flavored and tastes far better.) Wanted to know if Hemp oild would give me similar results as CBD.

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