I have had several neurological conditions like Bells Palsy three times, double vision, paralysis of left side of tongue. I have a lot of relief whenever I have pain by taking an inflamattory drug etoshine90 mg. Presently I have started taking Steroids for my facial palsy. The various pains I was having on the left side of neck, below the left ear, dizziness, pain around the head have subsided immidiately after the first dose of prendisolone 60 mg.I have read that CBD hemp oil can be useful for my condition of neurological and inflammation issues. My question is what concentrate (mg) of the oil should I take and for how long. Any brand that you may suggest that are available in the UK. Thank you.
Cannabidiol (CBD) oil is essentially a concentrated solvent extract made from cannabis flowers or leaves that is dissolved in an edible oil such as sunflower, hemp, or olive oil. Solvents used can vary from relatively innocuous organic solvents (ethanol, isopropyl alcohol) to more harmful ones (petroleum-ether, naphtha), or even supercritical fluids (butane, CO2). The exact conditions and solvents applied have a great impact on, for example, the taste, color, and viscosity of the final product. Because many other plant components are co-extracted with the desired cannabinoids present in the herbal material, these are sometimes removed by a treatment known as “winterization.” By placing the extract in a freezer (–20 to –80°C) for 24–48 h, components with a higher melting point such as waxes and triglycerides, as well as chlorophyll will precipitate, so they can be removed by filtration or centrifugation [1]. This treatment can significantly improve the taste and color of the final product.
People suffering from other neurological disorders might also benefit from using CBD oil as part of their treatment. Several studies involving Parkinson’s disease showed that participants slept better after treatment. Furthermore, their overall quality of life increased. Amazingly, CBD also showed positive benefits in treating or preventing Alzheimer’s disease. As CBD lowers inflammation, it helps prevent nerves from degenerating. During one study, scientists used mice with the genetic predisposition for Alzheimer’s disease. They found that CBD helped by preventing the mice’s cognitive decline.
...with due respect, your experience Locsta is almost precisely what happened with my....chihuahua. Degenerative disc disease, excruciating pain, prednisone worked, but couldn't keep her on it..pain killers and muscle relaxants didn't help, really thought I would have to put her down. Chi bloggers suggested CBD; gave PetReleaf a shot--like you, literally within minutes I could see the difference, in days she was pain free and now is back in charge of our world. The real key here is that with my dog, there is zero, nada, chance that there was any placebo effect...
CBD has positive implications in a vast number of illnesses and has been shown to boost general health, hair and skin.  Research isn’t conclusive here, although it is strong, and in the coming years, we are expecting to see more and more evidence.  THC, on the other hand, can benefit other disorders but comes with drawbacks, such as the feelings of being high and possible induction of feelings of anxiety and paranoia and more.
This peach-hued sea salt soak is the perfect Sunday afternoon bath ritual—and unlike a trendy bath bomb, it won’t turn your tub water a different color. With ingredients like magnesium flakes (stronger than Epsom salts), pink Himalayan salt, arnica, and of course, CBD extract, these crystals provide proactive therapeutic relief while also relaxing your senses with lavender and clary sage essential oils. You can also use them to soak your feet after a long run, just as you would with Epsom salts.
This has been the year medical cannabis hit the mainstream. The government has announced that it is relaxing laws on when cannabis medicines can be prescribed by doctors, following high-profile cases such as that of Billy Caldwell, the 13-year-old boy hospitalised by his epileptic seizures after he was denied legal access to the cannabis oil that helps control them. Meanwhile a new generation of cannabis medicines has shown great promise (both anecdotally and in early clinical trials) in treating a range of ills from anxiety, psychosis and epilepsy to pain, inflammation and acne. And you don’t have to get stoned to reap the health benefits.
I am currently going through red skin syndrome/topical steroid withdrawal. The only cure as of now is time(6 months to 3 years) and waiting out horrible eczema-like flares. My main issue is burning/tingling skin that is almost constant. Steroids close off blood vessels and when you stop them they 'wake' up causing this nerve discomfort/pain. I've been smoking medical cannabis for the duration of my recovery(1.5 years) and It's done wonders except that the flare is around my mouth and I'm afraid the smoking is causing more issues.. as well as helping. I need to step up my game and take a different approach. I am wondering how to go about using cbd but I don't know where to start and was wondering if you could help. Thank you
The few CBD studies out there give us limited information, and hardly any about recreational CBD use. One study gave people different amounts of ingested CBD (100, 300, and 900 mg), as well as, for comparison, a placebo and Klonopin; those people then had to give a public speech, an action associated with high levels of anxiety in the broad populace. Neither 100 mg nor 900 mg, nor the placebo, had any effect. The 300 mg dose, though, did have a measurable calming effect on heart rate, blood pressure, and anxiety. (The Klonopin also worked.)

As noted in the previous section, CBD oil prices vary significantly by brand. The best practice for most is to determine a per-milligram budget for CBD oil, as well as a maximum price for the entire bottle. For example, you might decide that 10 cents per milligram or less is a reasonable budget; and that $45 (for a 450-mg concentration, based on the budget) is a maximum bottle price. Also, if ordering online, be sure to include potential shipping costs.
I’ve been hoarding Girl Scouts Thin Mints lately (they’re especially good if you freeze them)—the chocolate is fine, but the peppermint oil is what makes them addicting enough to go through a whole sleeve without getting sick of them. I’m also trying to cut down on sugar, though, and while it would be a huge stretch to say that this peppermint oil-infused clear lip balm is a direct replacement for Girl Scout cookies, it really does have a very satisfying full-mouth taste of peppermint. The CBD oil, which soothes and facilitates healing at the same time, makes this formula an ideal balm for outdoor enthusiasts and or just those who are prone to painfully chapped lips. For those of us with long-hair-don’t-care, it’s not sticky—as a matter of fact, the formula is on the stiff side and won’t cause your hair to stick to your face, a welcome departure from many balms.

Many people take CBD oil for joint pain or even muscle soreness, but most would suggest that they are not as soothing or fast-acting as applying a topical CBD cream directly to the site of pain or soreness. Using a topical CBD cream for muscle soreness is also effective due to the simple mechanical effects of massaging. When you massage sore muscles, what you’re actually doing is stimulating the fibers in the contractile tissue to engage in capillary action; in other words, the fibers are actively exchanging expended blood and replenishing themselves with a new, freshly-oxygenated supply from arterioles.

In most cases (and in all cases in which the coffee shop doesn’t want to risk being sued), coffee shops can’t advertise CBD as doing much of anything, one way or another. While clinical trials attempt to determine an effective dose for a particular condition, says Esther, the growing “wellness empire” is free to leave the effects to your imagination. “People who are selling CBD don’t even have to make specific claims. The relationship between the actual amount of CBD and the effect doesn’t have to be very specific, because there is no specific effect that they’re talking about,” says Blessing. “So if I have a CBD latte, I might feel a little relaxed, or a little less neurotic, or who knows.”


CBD creams are produced with the extracted oils from cannabis or hemp infused into a topical base. They act upon the body’s naturally occurring CB2 receptors by binding with these components. The CB2 receptors are activated by either the body’s own, already present endocannabinoid system (ECS), or through the presence of phytocannabinoids, which are typically in the form of either CBD or THC.
A 2017 article published by the National Academies of Sciences, Engineering and Medicine conducted a study in which the results concluded, “In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.” This statement is quite a massive development for the increasing of tolerance towards CBD and CBD based products.
It is well known that cannabis plants obtained from uncontrolled sources may be contaminated with various harmful substances [39], sometimes leading to severe health issues or hospitalization [40]. Contaminants include chemicals that were intentionally added in order to increase yield, weight, or potency (e.g., pesticides, metal particles [41], synthetic cannabinoids [42]) but also agents that entered the plant unintentionally (e.g., heavy metals, molds and bacteria [43], aflatoxins). For example, pesticides are frequently present in cannabis sold by Dutch coffee shops [44], but were also found in cannabis offered under state law in California [45] as well as medicinal cannabis from licensed producers in Canada [46]. If any of these contaminants were present in hemp used for CBD extraction, they would likely end up in a concentrated form in the final oil. One contaminant specifically relevant to cannabis (CBD or THC) oils is the residual presence of toxic solvents used during the extraction procedure [3].
Oh, was I just talking about Girl Scout cookies? I prefer showers over baths—we all have an allegiance to one or the other—but we can’t ignore how many memes have come out of #bathbombs. It’s satisfying to watch them fizzle, they turn your bath into fun colors, and they claim to provide aromatherapy benefits, too. They’re also much tidier than traditional bath salt products; just chuck one in and wait!
Everyone wants a piece of CBD, and nobody is watching. Remember: There’s no regulation by the FDA or anyone else. An investigation by Natural Products Insider, a trade publication for the supplement industry, revealed that CBD producers are, at best, claiming to follow “good manufacturing practices” without any official oversight. It’s illegal to sell something that isn’t what its packaging claims it is — that falls under the purview of the Federal Trade Commission — but nobody is doing onsite testing.

Plus CBD Oil™ products come in a variety of flavors and concentrations to suit your preferences. If you are considering CBD oil for your health, as with any supplement, we encourage you to speak with your physician and dive into the research to learn more about this promising phytonutrient. We at Plus CBD Oil™ are proud of our innovative selection of products.
Zuardi, A. W., Crippa, J. A., Hallak, J. E., Bhattacharyya, S., Atakan, Z., Martin-Santos, R., … & Guimarães, F. S. (2012). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation [Abstract]. Current Pharmaceutical Design, 18(32), 5,131–5,140. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22716160

“Research shows that CBD content decreases when it is exposed to heat. It’s likely that the reduction in efficacy is due to the lower content. For instance, studies show that 71 degrees F can accelerate the degradation of CBD in a solution, resulting in less CBD. Potentially adding CBD to hot coffee may degrade it and reduce the amount of CBD available for absorption."

The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from organic hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.


The limited studies out there indicate that CBD has, in its various interactions with the brain and immune system, some anti-inflammatory and anti-anxiety effects. It can balance out the effects of THC by reducing the anxiety THC sometimes brings, and many in the industry are big on “broad spectrum” or “full spectrum” configurations, which use many cannabinoids at once.
I used it on my mother's feet (she's 90). She is great for testing anything because she's in an incredible amount of pain and absolutely NOTHING works for her. Two hours after I applied it, she came into my room and said, "I can't believe that cream actually worked. I still don't have any pain in my toes and the bottom of my feet. It worked so well, I forgot about the pain after you put it on..." Needless to say, she looks forward to an application every evening.
Yes, there's a new type of topical ointment on the market, and it's infused with the cannabidiol (CBD) from marijuana. Manufacturers claim it can help alleviate acute pain and muscle soreness. CBD is similar to THC, except it's non-psychoactive, meaning some researchers view it as the golden child of medicinal use. (See also: Personal Trainers Reveal the Products They Use to Relieve Muscle Soreness)
It’s important that you are applying the CBD topical to areas of the skin that are unaffected by other skin-care products. Making sure that you are applying your topicals to clean, product-free skin ensures that your skin is effectively absorbing the oil in its entirety. Mixing CBD oil with other products will only dilute the effects and reduce its effectiveness.
CBD, one of the more than 100 chemicals in cannabis, is emerging as a popular wellness ingredient. The plant extract, often consumed as an oil under the tongue, is now the featured ingredient in high-end products including coconut oil, body lotion, face serum, olive oil, jam, bath scrub, cold-brew coffee, sports salve, lip balm, infused water, gummy snacks and dog treats. Products' prices vary but may cost about triple what their CBD-less counterparts do.
Not only are we all made differently, we each have our own unique history with the use of substances, medications, supplements, and other things we put in our body. Because of this, we all have different body chemistry, and this will affect how our body reacts to CBD. As R.R Noall over at Herb puts it, “what works for your friend, may not work for you.”

Most CBD oils are available in round-number concentrations such as 250mg, 500mg, and 1,000mg. While these strengths accommodate many CBD users, they may not be sufficient for those with preferences that fall outside round numbers. NuLeaf Naturals offers a less conventional selection of concentrations: 240mg, 725mg, 1,450mg, 2,425mg, and 4,850mg. This range ensures that most users will find a strength that works for them.
Like many of my fellow New York City residents, I’ve recently grown aware of the presence of CBD in my surroundings. In particular, CBD at coffee shops. It started when some friends of mine were discussing a pilgrimage out to Flower Power Coffee Co., known for its “artisanal CBD-infused coffee.” Then, at a fancy matcha cart I went to for Instagram-related purposes, I noticed that alongside health food add-ins like oat milk was the option to include a one-dollar shot of CBD. I didn’t do it, because weed in most forms tends to make me sleepy and it was 1 p.m. on a Saturday in the middle of Brooklyn's trendiest neighborhood.
Let’s start by looking at THC.  THC (tetrahydrocannabinol) is the compound found in cannabis with psychotropic properties.  Medical marijuana companies breed their plants to have the highest concentrations of this compound.  It is associated with the feeling of being high that marijuana smokers experience.  Effects include feelings of euphoria, pain relief and sometimes increased anxiety and paranoia.

Most users find that regular application provides an analgesic effect that significantly reduces localized discomfort.2 Even though CBD is most often taken for pain relief, research is showing it to be beneficial in relieving, cramps, headaches, and psoriasis. CBD’s effects can increase the natural levels of pain-relieving endocannabinoids, decrease inflammatory responses, and desensitize pain receptors.2


Return Policy: Once order has been received and you are not satisfied with the product within 30 days of purchase you may return for full refund. Any manufacturer defects or issues on the part of the manufacturer, you may return for a replacement or refund within 30 days of purchase. Pricing and specials are subject to change. Please reach out to your Rep or Sales Manager with any questions regarding the product. Please be aware that the products may contain essential oils and infused herbs, therefore if you have any allergies to such please do not use.
A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[68][69] Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions.[70] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[70] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[70]
Be careful to check the nutritional info. On back of bottles. While some brands boast of high mg.s that is for the whole bottle. I use a brand that is 2 oz. 100 mg. Pet dose. A dose is 3 drops. I’ve seen some boast of 700 mg. Or more, but you read on back that a dose is 20 drops for 10 mg. Of help oil. That 700 is the whole 1oz. Bottle and cost twice what I pay for a 2 is bottle.
Laboratory evidence indicated that cannabidiol may reduce THC clearance, increasing plasma concentrations which may raise THC availability to receptors and enhance its effect in a dose-dependent manner.[25][26] In vitro, cannabidiol inhibited receptors affecting the activity of voltage-dependent sodium and potassium channels, which may affect neural activity.[27] A small clinical trial reported that CBD partially inhibited the CYP2C-catalyzed hydroxylation of THC to 11-OH-THC.[28]

So is it possible that despite all this anecdotal evidence, low-dose CBD is a placebo? Sure, because, say it with me: We don’t know anything about CBD. “Unfortunately,” says Baron, “we are nowhere near close to having any definitive trials on effectiveness for most symptoms claimed to benefit from CBD with trials that are scientifically relevant, such as prospective randomized placebo-controlled trials.”
Long time NYC resident (over two decades) and underground DJ, Ian Ford,  is the creator and owner of the Caffeine Underground! Ford took his passion for music and exposed audiences to new soundscapes and cultures through his successful DJ residencies at some of NY's most infamous clubs including The Bank, Webster Hall, Splash, XL and many more. Through the buzzing metropolis, Ford was able to see into the darkest corners of night life and helped support his local communities who were a part of LGBTQIA, rock and electronic dance scenes. Ford spent much of his time over the years developing a lifestyle that was grounded, and more healthy. He began studying topics in spirituality, martial arts, and physical training. Since then, Ford still practices and is an educator in PaKua Martial Arts, Reiki, and Ch'ien Chi Kua. Ian Ford continues to spread his wealth of culture, sharing his insight and joy with others in the hope, they continue to share their own experiences.
Although THC is best known for its mind-altering euphoria, it too has important medical benefits. There’s some overlap in what CBD and THC can treat, but THC is particularly effective in relieving nausea, appetite loss, insomnia, among other symptoms. Many patients find that a balance of CBD and THC offers the best symptom relief as the two work together synergistically.
The second method of pain relief centers around the damage you do when you work out. When you strength train, you create micro-tears in your muscles, which is why you feel sore as you heal. Once your immune cells detect damage, they release inflammatory mediators in order to repair the tissue. CBD, though has the ability to limit the release of some proinflammatory signals, thereby helping with pain without thwarting the healing entirely, Gerdeman explains.
THC, tetrahydrocannabinol, the substance responsible for the psychoactive effects for marijuana we associate with getting high, comes with side effects such as reduced short-term memory, impaired thinking and potential anxiety, while CBD, cannabidiol, possesses therapeutic effects such as relief of pain, stress, depression, Alzheimer’s, epilepsy, as well as protecting those parts of the brain associated with memory and learning. CBD's positive effects are due to its ability to bond with receptors in the brain, hence the anti-anxiety, anti-spasmodic and neuroprotective effects, as well as receptors throughout the body, lending itself to anti-inflammation and pain relief. 

I was diagnosed with fibromyalgia,chronic pain and arthritis a few years ago. I suffer 24/7 with pain all over my body. I’ve also been diagnosed with type two diabetes last month . I’m at my whits end with everything,the amount of medication and the things I’ve had to give up. A doctor over heard what my condition was and suggested i try cbd as it doesn’t contain thc and could be quite beneficial for me. My trouble is i’m in the UK and our law is very outdated and cbd isn’t as easy to get hold of. It’s not like i can just walk into a chemist and pick some of the shelves. Can anyone recommend someone or somewhere i can obtain this cbd to try and see if it helps me. I’ve been told you can get it to put in an ecig which would be useful as i use them. Thank you and sorry if i dragged on

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