He emphasises that the company’s products are “whole-plant extracts that include a variety of phytochemicals, not just CBD. These beneficial compounds include a range of phytocannabinoids, terpenes and flavonoids that work together.” This isn’t necessarily seen as a positive by researchers, with McGuire saying: “They muddy the water.” However, Sativex is also a plant extract containing other cannabinoids and substances. David Potter, chief botanist at GW Pharmaceuticals, which makes the drug, says the evidence at the time the drug was developed “suggested there was a synergy between these active ingredients”.

One study found that placebos sometimes work even when the subject knows it’s a placebo. Another, using that same public speaking setup that CBD studies have used, found that anxiety treatments are particularly susceptible to the placebo effect, with 40 percent of placebo-treated patients showing a decrease in anxiety symptoms while tasked with speaking to a crowd.
On a sunny but unseasonably freezing April afternoon in New York, I walked the 10 or so minutes from the L train to Caffeine Underground, a coffee shop in Bushwick that triples as an art gallery and community center. The open-concept space serves lattes and espressos and a variety of milks (oat, almond, macadamia) and plenty of “wellness” options (Kava tea, Bulletproof-style coffee, activated charcoal add-ins). But there’s one totally unique item: Cannabidiol-infused (CBD) coffee.
My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?
Last but not least, the starring ingredient. I have both variations (Olive Oil and Mint Chocolate) of Charlotte's Web, and I've used both in my coffee mixtures. The Olive Oil flavor is invisible among the mix-ins. When I first began making my CBD coffees at home, I started in baby steps, using just a few drops and eventually graduating to one full dropper. It's totally up to each individual, and while the packaging says one to three droppers per day is recommended, I've found my sweet spot to be just the morning single. I simply squeeze a full dropper into my blender with the rest of my ingredients, add a few ice cubes, and blend until smooth. I'm obsessed with the Mint Chocolate flavor and also add it to smoothies. As with anything you ingest, especially supplements, it's important to be careful with sourcing and to know what you're ingesting. I 100% trust Charlotte's Web for providing a healthy and safe product. Again, this is what has worked best for me, but if you're interested in trying CBD in your coffee (or any CBD product for that matter), doing your research and experimenting with what feels comfortable and tolerable to your body and its sensitivities is crucial. 
Everyone needs a lip balm in a tube for on-the-go situations, and Colorado-based Ambary Gardens made a clear version with a faint lemon scent and only seven ingredients including CBD extract. It doesn’t leave your lips glossy or shiny or sticky—it just adds a layer of hydrated protection on the surface of your lips. While I’ve yet to try this on chapped lips, I imagine it’s a quick fix for quick relief, no glossy residue left behind.
Because it does not produce psychoactive effects and hemp is not a controlled substance, hemp-based products are legal to sell, buy, and possess in all 50 states. However, the law is a bit more complex when discussing CBD oils and other hemp byproducts. According to the 2014 Farm Bill, hemp should only be grown and cultivated for academic research purposes. This means that, technically, any hemp-derived oil that is not grown for these purposes would be illegal — though this law is rarely enforced. To make matters more complex, the laws are somewhat unclear in certain states. Sen. Mitch McConnell of Kentucky recently introduced legislation that would legalize all hemp products at the federal level, but this decision is still pending.
Given the degree to which marijuana and cannabinoid derivative use has been stigmatized in the past, their Schedule I classification as illegal substances, and lack of FDA approval, valid medical research on the effects of CBD isn’t as plentiful as it should be. Much of the anecdotal evidence, however, suggests that CBD’s neuro- protective, analgesic, and anti-inflammatory effects with regard to topical applications are promising.2
Mike, what kind of breast cancer (invasive ductal, I presume)? How many of her lymph nodes were positive? How big was the primary tumor? Reason I ask is that in women with Stage I or IIA tumors that are estrogen-and progesterone-receptor-positive and HER2-negative (ER+/PR+/HER2-) with three or fewer positive lymph nodes, there is a genomic assay test on a sample of the tumor, called OncotypeDX, that will tell doctors whether chemo is necessary or would even work at all. Medicare covers that test 100%.That type of breast cancer mentioned above, which I had as Stage IA, is treated in postmenopausal women with anti-estrogen drugs called aromatase inhibitors(aka AIs: anastrazole, letrozole, or exemestane)which have as a side effect joint pain. CBD oil is effective for this joint pain it is not, I repeat, NOT a substitute for chemo, radiation or these anti-estrogen drugs.So don’t assume your mom’s cancer will require chemo; but if it does, CBD helps with those side effects as well. If she lives in a state where medical marijuana is legal, there are doctors who sub-specialize in certifying applications for a medical marijuana card, and in the interim before the card is issued can advise as to the appropriate dose of CBD oil (legal and over-the-counter in all 50 states). Some (though not most) medical oncologists will certify their own patients’ medical marijuana card applications so she need not seek out another doctor; and will advise the appropriate dose for her symptoms. Once she gets her card, the “budtenders” in the licensed dispensaries can advise her as to the right CBD product (with or without THC), strength, and dosage. If she lives in a state where recreational weed is legal, the “budtenders” in the marijuana shops can steer her to the right strength of CBD oil and the right dosage.
CBD has also shown promise to reduce cravings among people addicted to opioids, according to a study published in Neurotherapeutics in 2015. It may fight cancer, too. The authors of a review published in the British Journal of Clinical Pharmacology in 2012 wrote: “evidence is emerging to suggest that CBD is a potent inhibitor of both cancer growth and spread.”
Hemp Extract- A Canadian hemp oil extract with naturally occurring terpenes, flavonoids, and other beneficial phytonutrients extracted from the hemp plant. This CO2 extracted hemp oil is free of harmful solvents and uses a gentle, low temperature, alcohol free extraction process that yields the purest form of hemp oil extract available. This clean oil extraction process yields a high quality extracted hemp oil retaining a broad spectrum of terpenes and other phyto compounds derived from the Cannabis Sativa industrial hemp plant. This does not contain THC and is legal in all 50 states. 

So far, by far the best medicinal relief I have found for my systems is a particular strain of cannabis flower called Harlequin — it contains an almost 3:1 ratio of CBD:THC, which is extremely rare and unique in the cannabis world. There are multiple studies you can find online showing the SYNERGISTIC effects of CBD combined with THC. When they are used together, they are much more medicinally effective than other one is on their own. Most cannabis strains today have zero CBD because growers realized everyone just loves their THC, but the Harlequin strain is a god send.


The term "CBD" is a nickname for cannabidiol, which is one of several cannabinoids, or chemical compounds, that are found in cannabis and hemp plants. Of course, the most famous cannabinoid is tetrahydrocannabinol, or THC, which is the main psychoactive component in marijuana (aka, the part that gets you high). Because CBD is not psychoactive, it does not create the same buzzy effects typically associated with marijuana when ingested.
Having run infusion workshops in Denver for the last 3 years, I have played with several recipes. Just Add Herbals has kits that include hypoallergenic mediums that you can infuse with kief, which they give you a way to extract from cannabis. Even lower quality cannabis can be used, the key is to pay attention to the genetic you are using. Kief makes dosing easier and these kits are a simple way to infuse not just salve, but tincture, massage oil, and cooking oil as well. The salve may be ideal for folliculitis – I’d be curious to hear how it does for you.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.

But, uh, what is it that CBD is supposed to do? I visited a cannabis dispensary in Boulder to find out what the hype was all about. After passing an ID check, I was introduced to a “budtender” who pointed me to an impressive array of CBD products — tinctures, skin patches, drink powders, candies, salves, massage oil, lotions, “sexy time personal intimacy oil” and even vaginal suppositories to treat menstrual cramps.
CBD, one of the more than 100 chemicals in cannabis, is emerging as a popular wellness ingredient. The plant extract, often consumed as an oil under the tongue, is now the featured ingredient in high-end products including coconut oil, body lotion, face serum, olive oil, jam, bath scrub, cold-brew coffee, sports salve, lip balm, infused water, gummy snacks and dog treats. Products' prices vary but may cost about triple what their CBD-less counterparts do.

I suffer fr migraines. Currently having Botox injections every three months for the last three years. This has helped went fr 24 to 30 migraines a month to 6 to 8 , now I'm back up to 14 to 20 a month. My doctor thought CBD oil might help. I have also started having anxiety attacks for a year now. I'm really confused with the dosages. Any thoughts would b helpful


In the last 6 months, I have been experimenting with CBD & THC to treat the aforementioned. It’s been an expensive experiment with some improvement, just not enough relief from the pain. I’m currently using 75 mcg of fentanyl transdermal, 30 mg Oxycodone 5x daily, muscle relaxers, arthritis pills, etc and they still don’t get me out of bed most days.
The 2016 European Journal of Pain conducted a study on rat models to test the effectiveness of CBD against arthritis in order to see if it could serve as an all-natural alternative to the typical arthritis pain medications, which are often tied with numerous uncomfortable and frustrating side effects. The rats were treated for 4 days with 4 different doses of CBD gel, and the results were quite staggering.
I have pre cancer and cancer spots on my head and face. I have been going to my dermatologist for over 5 years every 1-2 months to have them either frozen to stop there spread or surgically removed. Since I started using CBD cream I have reduced all of my skin spots and have not needed any surgery for the last 6 months. I have very NO spots that need freezing either. I am SOLD on this product as it DOES work for me.
Last year, the National Academies of Sciences, Engineering and Medicine released a nearly 500-page report on the health effects of cannabis and cannabinoids. A committee of 16 experts from a variety of scientific and medical fields analyzed the available evidence — more than 10,000 scientific abstracts in all. Because so few studies examine the effects of CBD on its own, the panel did not issue any findings about CBD specifically, but it did reach some conclusions about cannabis and cannabinoids more generally. The researchers determined that there is “conclusive or substantial evidence” supporting the use of cannabis or cannabinoids for chronic pain in adults, multiple sclerosis-related spasticity (a kind of stiffness and muscle spasms), and chemotherapy-induced nausea and vomiting. The committee also found “moderate” evidence that cannabis or cannabinoids can reduce sleep disturbances in people with obstructive sleep apnea, fibromyalgia, chronic pain and multiple sclerosis, as well as “limited” evidence that these substances can improve symptoms of Tourette’s syndrome, increase appetite and stem weight loss in people with HIV/AIDs, and improve symptoms of PTSD and anxiety.
Look up Chris Shade (quicksilver scientific) on YouTube, specifically a webinar entitled ‘Cannabidiol: The Full Story pt.2’. He is a brilliant biochemist who has been studying the biochemical effects of cannabidiol. He says that CBD has the potential to be more therapeutic than THC as it up-regulates/down-regulates gene expression in over 400 genes each way (up and down). A great balancer and extremely helpful in treating Lyme, more specifically allowing for more aggressive detoxification of the Lyme and co-infections. There is also considerably symbiosis with heavy metals, molds, EMF’s, etc. so you must also address those aspects. It’s supremely complex and even most Lyme literate docs don’t deal with all aspects. Antibiotics are often counterproductive with persistent Lyme as the spirochetes protect themselves with a biofilm that must be broken down (Interfase Plus). Protocols must be comprehensive in order to make progress. If you have not checked your CD57, do that. It’s a marker for natural killer cells commonly associated with Lyme (a simplistic explanation). The reference range is 100-300. First time I had it checked 2 years ago, it was 48. Despite modest attempts to boost my CD57 with some of the Nutramedix products, I only got 6-7 point increase per year. In April of this year, I got more aggressive with a homeopathic regimen, taking a variety of the Cowden (Nutramedix), Buhner and other products. The next time I checked CD57, two months later, it jumped 70 points… remarkable by any measure. My western blot also went from 2 bands to 5 bands as my body as finally able to mount an antibody response. I can’t say for sure which products had the biggest impact, but if I had to guess, it would be the Biocidin LSF (liposomal) and perhaps DesBio Lyme Plus. But I was also taking Samento, Burbur, Cumanda, resveratrol, glutathione, phosphatidylcholine, NanoMojo, and a variety of other things and a good supplement regimen. There is no one product answer. Cannabinoids can help with the symptoms and support a more aggressive regimen, but addressing the Lyme must be a multi-faceted effort. Be very wary of pulsed antibiotic protocols with doxycycline. It’s not out of the question, but decimating your microbiome is counterproductive.
Once the oil has been applied, massage it gently but firmly into your skin. The body won’t absorb much of the cannabinoid in small doses, so be sure to apply liberally. Once you’re done, make sure you wash your hands so you do not inadvertently spread potentially irritable substances to sensitive areas. Some oils contain substances that may cause discomfort and irritation to the wrong parts of the body, such as the eyes.
I LOVE my CBD pain cream. It is called “CAD” (short for Carter’s Aromatherapy Designs) cream. The downside is that it’s uber expensive ($45 to $140, for a 2 ounce jar, depending on the strength), but the little jar does seem to stretch quite a way. It smells of peppermint, not skunk. I’m currently experimenting with making my own from home-grown AC/DC. So far, I like the CAD better.

This mint-green bath bomb, made by Los Angeles-based De La Beuh, combines the invigorating aromatherapy of peppermint oil with the pain relief benefits of CBD. I sat in the bath with this bath bomb soak for an hour—until the water ran cold—when I had both cramps and lower back aches, and while it doesn’t beat ingesting a painkiller, it did help soothe my pains so that I fell asleep as soon as I hit the pillow. De La Beuh sells bath bombs in many varieties—including a glittery Kaleidoscope version that will turn your bath into “unicorn” colors—so your preference just depends on your preferred aroma.
Once the oil has been applied, massage it gently but firmly into your skin. The body won’t absorb much of the cannabinoid in small doses, so be sure to apply liberally. Once you’re done, make sure you wash your hands so you do not inadvertently spread potentially irritable substances to sensitive areas. Some oils contain substances that may cause discomfort and irritation to the wrong parts of the body, such as the eyes.
I recently discovered Après and have quickly become obsessed. I like to make sure I start my morning with protein, fiber, and fat, and their signature recipe features all of the above. Plus, it makes for a yummy and sturdier base for my favorite cold brew than just water or almond milk, my previous standbys. All of the flavors are great, but since the CBD oil I love is mint chocoate–flavored, I opt for the like-minded flavor of Après. Post-coffee and -ice, it's like a magical mint-chocolate shake that simultaneously wakes me up and calms me down. Kind of perfect, no? 
I suffered from severe eczema as a child and, thankfully, grew out of it for the most part. Eczema is skin with a weak barrier that makes the sufferer’s skin much more open to irritants and allergens, causing a lot of discomfort. This irritation/allergic reaction leads to itching, bacterial infections, over-moisturizing which can lead to yeast overgrowth, etc. Once the chain reaction is set off, it is very difficult to stop. As a child, my parents would come in after I went to sleep, slather my legs with aquaphor and wrap them in ace bandages. It was a sticky mess but somewhat effective. To soothe my dry and easily irritated adult skin (as well as my arthritis), I make a cannabis product wth beeswax, shea butter, coconut oil, and a handful of healing herbs. Beeswax is a great barrier/protectant and has other beneficial properties. The Shea butter is very similar to sebum in our skin so acts to supplement our natural protection.
A non-intoxicating, highly therapeutic compound in cannabis known as CBD, or cannabidiol, has sparked a revolution in cannabis. Studies have demonstrated CBD’s benefits in treating a variety of ailments, including epilepsy, cancer, pain, arthritis, and anxiety disorders, although it can also be used to alleviate everyday stress and more mild symptoms.
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