Recently, an interesting study performed in the Netherlands highlighted multiple issues that may be extrapolated to CBD products elsewhere [51]. In this study, 46 different cannabis oil samples were collected directly from patients and analyzed for cannabinoid content. The obtained samples were home-made (n = 29) or purchased from a (web) store (n = 17). For 21 of the 46 products (46% of all samples), label information was available on CBD/THC content, so that the claimed content could be compared to the analyzed content as determined in the study. Results are shown in Table 1. In many cases the analyzed cannabinoid content strongly differed from the claimed content on the label, while in 7 samples no cannabinoids (CBD or THC) were found at all. Such deviations were found in home-made as well as commercially obtained products.


I live in Utah so I have no way to get Harlequin CBD. Is there anything even close to that, that doesn’t need a medical card to purchase. There are so many BS CBD hemp companies that are not trustworthy and I don’t want to waste anymore money trying to find something. My son loves his school or we would have moved already. Help! I need a legit CBD hemp company to buy tincture and capsules. Leafy is my go to because so far all the info always checks out.
Can anyone tell me if this is good for extreme IBS and if so what is the best one and should it contain both CBD and THC ? Also what is the strongest/best oil capsule to use? Where to purchase? My son started using CBD only oil 3 days ago and nothing has changed in he’s symptoms which makes me think he needs THC as well? Can anyone help I’m desperate!!!! Many thanks
Though a CBD latte might not do much for you — at least not beyond what caffeine and the placebo effect combined can do, which isn’t nothing — it’s also probably harmless in most cases, says Carson, and may even have positive benefits we aren’t yet aware of. “I suspect there’s probably some antioxidant benefit to CBD like there is with coffee,” says Carson. “There’s tons of good things in coffee that we still don’t fully understand, and I think the marijuana plant is much the same way.”

CBD Topical Lotions


“CBD inhibits the cytochrome P450 enzymes that break down important psychiatric drugs,” says Blessing. CBD isn’t the only substance that messes with the body’s ability to metabolize these drugs — both St. John’s wort and the humble grapefruit are unfriendly — but CBD is comparatively poorly studied. The way CBD inhibits those enzymes could dramatically raise the levels of SSRIs or opioids in the system, potentially leading to an overdose.
^ Hayakawa K, Mishima K, Hazekawa M, Sano K, Irie K, Orito K, Egawa T, Kitamura Y, Uchida N, Nishimura R, Egashira N, Iwasaki K, Fujiwara M (January 2008). "Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB(1) receptor-dependent mechanism". Brain Research. 1188: 157–64. doi:10.1016/j.brainres.2007.09.090. PMID 18021759.
Industrial Hemp Oil is also from the Cannabis Sativa plant and is the same as Hemp Oil or Hemp Seed OIl. Compared to cannabis Indica, cannabis Sativa (industrial hemp variety) has a much stronger fiber. This fiber can be used in anything from rope and blankets to paper. Marijuana fiber has a low tensile strength and will break or shred easily, making it a poor fibrous plant when compared to industrial hemp. Industrial hemp has low THC levels compared to marijuana specifically cultivated for personal psychoactive use. The reason for the low THC content in hemp is that most THC is formed in resin glands on the buds and flowers of the female cannabis plant. Industrial hemp is not cultivated to produce buds, and therefore lacks the primary component that forms the marijuana high. Furthermore, industrial hemp has higher concentrations of a chemical called Cannabidiol (C B D). 

This attention to detail extends to our carefully curated selection of CBD topical products. It’s incredibly important to us that you feel confident in your next CBD purchase, and if you’re ever unsure about anything related to CBD, our friendly and knowledgeable support team are only a click away. Browse our range of CBD salves, ointments, and other topicals, or get in touch if you have any questions.
THC, tetrahydrocannabinol, the substance responsible for the psychoactive effects for marijuana we associate with getting high, comes with side effects such as reduced short-term memory, impaired thinking and potential anxiety, while CBD, cannabidiol, possesses therapeutic effects such as relief of pain, stress, depression, Alzheimer’s, epilepsy, as well as protecting those parts of the brain associated with memory and learning. CBD's positive effects are due to its ability to bond with receptors in the brain, hence the anti-anxiety, anti-spasmodic and neuroprotective effects, as well as receptors throughout the body, lending itself to anti-inflammation and pain relief. 

CBD does not appear to have any psychotropic ("high") effects such as those caused by ∆9-THC in marijuana, but may have anti-anxiety and anti-psychotic effects.[10] As the legal landscape and understanding about the differences in medical cannabinoids unfolds, it will be increasingly important to distinguish "medical marijuana" (with varying degrees of psychotropic effects and deficits in executive function) – from "medical CBD therapies” which would commonly present as having a reduced or non-psychoactive side effect profile.[10][60]
Outside of CBD I would ask however have you tried having him change his diet? If the IBS is food allergen related, as some studies are starting to show, CBD and the like are only effective at calming some of the symptoms. The most effective treatment is aimed at figuring out what is causing the issues to begin with by starting a food diary and instituting dietary changes. Look into a diet called “The Whole 30” to see if it’s a particular food or food type that is causing aggravation of symptoms. For many people things like Gluten, Dairy, Meat, and/or processed foods are the offending culprits and cutting these out of the diet can result in greatly reduced symptoms and improved quality of life.
But, uh, what is it that CBD is supposed to do? I visited a cannabis dispensary in Boulder to find out what the hype was all about. After passing an ID check, I was introduced to a “budtender” who pointed me to an impressive array of CBD products — tinctures, skin patches, drink powders, candies, salves, massage oil, lotions, “sexy time personal intimacy oil” and even vaginal suppositories to treat menstrual cramps.

I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.


Hey Yani- I’m up in WA and had acquired a topical oil made by a friend that worked wonders on angry joints. I know they started from leaf to create. I’m not capable of doing that and am wondering if you have recommendations for resources how to make my own salve from concentrate. I make my own coconut oil/essential oil mixtures already… I’m just not entirely certain where to started with adding in CBD/THC.
Royal Queen Seeds CBD Oil offers a convenient, discreet and quick way to dose yourself with a bit of CBD, no matter your situation or where you are. All of our CBD oil is created using organically grown hemp sourced from right here in Europe, extracted using the latest CO² techniques. It means our oil is 100% natural, offering pure and strong CBD. All you need to do as drop you dose under your tongue or in your food, and away you go!

It is well known that cannabis plants obtained from uncontrolled sources may be contaminated with various harmful substances [39], sometimes leading to severe health issues or hospitalization [40]. Contaminants include chemicals that were intentionally added in order to increase yield, weight, or potency (e.g., pesticides, metal particles [41], synthetic cannabinoids [42]) but also agents that entered the plant unintentionally (e.g., heavy metals, molds and bacteria [43], aflatoxins). For example, pesticides are frequently present in cannabis sold by Dutch coffee shops [44], but were also found in cannabis offered under state law in California [45] as well as medicinal cannabis from licensed producers in Canada [46]. If any of these contaminants were present in hemp used for CBD extraction, they would likely end up in a concentrated form in the final oil. One contaminant specifically relevant to cannabis (CBD or THC) oils is the residual presence of toxic solvents used during the extraction procedure [3].
So far, by far the best medicinal relief I have found for my systems is a particular strain of cannabis flower called Harlequin — it contains an almost 3:1 ratio of CBD:THC, which is extremely rare and unique in the cannabis world. There are multiple studies you can find online showing the SYNERGISTIC effects of CBD combined with THC. When they are used together, they are much more medicinally effective than other one is on their own. Most cannabis strains today have zero CBD because growers realized everyone just loves their THC, but the Harlequin strain is a god send.
McGuire doesn’t advise buying CBD products. You need to differentiate, he says, between the extremely high doses of pharmaceutical-grade pure CBD that participants in the handful of successful studies were given and the dietary supplements available over the counter or online. “These may contain quite small amounts of CBD that might not have large enough concentrations to have any effects,” he says. “It’s the difference between a nutraceutical and a pharmaceutical.” These supplements aren’t allowed to make claims of any effects. “If you’re making creams or sports drinks with CBD, you can say anything you like as long as you don’t say it will do such and such,” he says.
CBD oil is most readily available as a tincture. This can be taken by applying a few drops under your tongue, holding in your mouth for a few moments so it can be absorbed, before swallowing. It can also be added to water or smoothies. A spray form is available (simply spritz under your tongue), as are capsules, creams that can be applied topically, and e-liquid for vape pens.

Next up, collagen! The Après already has 13 grams of plant-based protein in it, but to give me an extra hit of endurance for a full morning and eventual workout, I like to supplement that with one or two scoops of collagen peptides. The mix is tasteless, blends smoothly, and lends extra creaminess, which I love. Plus, I've seen a marketable difference in the health of my skin, hair, and nails since regularly incorporating collagen into my diet. 
The CBD oil needs to be taken twice a day everyday. The dosage depends on symptoms and it takes 30 days to awken your natural cannabis system after you begin taking the oil. I personally use Hemp works CBD oil in the 750 strength and only need 5 drops sublingual 2 times daily and results are many. Problem with oil and alz.patients is getting them to hold oil under tongue for 60 seconds. We have just began to get my dad on it. He too is in a nursing home in the state of florida and they cannot deny him any medication my mom has requested that he receive. If she is not their they are supposed to administer and she will call them to make sure he gets it. He is not 30 days into dosing yet so I don't have any results to speak of. I do know that since he has started he has had no more bladder infection and has not fallen in 3 weeks. That's a record for him so we will continue to monitor. Best of luck to you and a lot is going to depend on the state your mom is in and what the state laws are concerning her rights or the rights of whom has her medical power of attorney

Next up, collagen! The Après already has 13 grams of plant-based protein in it, but to give me an extra hit of endurance for a full morning and eventual workout, I like to supplement that with one or two scoops of collagen peptides. The mix is tasteless, blends smoothly, and lends extra creaminess, which I love. Plus, I've seen a marketable difference in the health of my skin, hair, and nails since regularly incorporating collagen into my diet. 
CBD products have become increasingly popular in recent years, as more and more producers market CBD as the new "it" drug for the health and wellness set — one that has been touted as a pain reliever and a treatment for anxiety, among other potential applications. Last year, consumer sales of CBD products topped $350 million in the United states, more than triple the amount sold in 2014, and various estimates predict the market could reach $2 billion within the next two to four years.
The 2014 Farm Bill[74], legalized the sale of "non-viable hemp material" grown within states participating in the Hemp Pilot Program[75]. This legislation defined hemp as cannabis containing less than 0.3% of THC delta-9, grown within the regulatory framework of the Hemp Pilot Program. This has led many to insist that CBD manufactured from hemp, is legal in all 50 states and exempts its oversight by the DEA as a controlled substance[76]. The 2018 Farm Bill is anticipated to provide further clarity regarding hemp regulations[77].
Cannabis has been used for centuries to treat nerves and anxiety, as well as other mood problems. CBD may help to improve both depression and anxiety, at least in part through its interactions with serotonin receptors in the brain. Research shows that CBD can reduce both mental and physical symptoms of anxiety. A study of CBD given to people before a public-speaking event indicates that CBD can help reduce stress—this and other research has shown that CBD can be an effective treatment for social anxiety.
Effective in January 2017, the DEA (which typically refers to marijuana by the plant’s scientific species name, Cannabis sativa, or the Reefer Madness-era spelling “marihuana”) made a rule stating its marijuana scheduling includes “marihuana extract.” In the rule, the agency defined “marihuana extract” as an “extract containing one or more cannabinoids that has been derived from any plant of the genus Cannabis”—which would include CBD.
In general, most people who’ve made the jump to drinking CBD coffee every morning claim they’ve done so because it allows them to simply have a better day and live a better quality of life. That is to say, their chronic pain is subdued, their mood and state of mind is elevated, and their general sense of physical and emotional well-being is improved.
Dispensaries: In states where marijuana is legal for recreational use, dispensaries are a common sight. They are much rarer in states with more restrictions. In states that permit the use of medical marijuana, hemp-based CBD oils do not normally require a prescription but marijuana-based oils do. Like brick-and-mortar locations, dispensaries offer more customer service. However, as noted, this may not be an option depending on the buyer’s state of residence. Also, CBD oil prices tend to be significantly higher at dispensaries.

I have lower back pain with some arthritis and arthritis in my hands.ive recently tried CBD Oil. It really does work. I have the drops and ointment. They both work. Because of the back pain I never would have been able to go on a hike with my family. We had a lot of fun. And "No Pain", all day. I'm also Type 2 diabetic. Anxious to see what my A1C is next month. I'm a believer.
Return Policy: Once order has been received and you are not satisfied with the product within 30 days of purchase you may return for full refund. Any manufacturer defects or issues on the part of the manufacturer, you may return for a replacement or refund within 30 days of purchase. Pricing and specials are subject to change. Please reach out to your Rep or Sales Manager with any questions regarding the product. Please be aware that the products may contain essential oils and infused herbs, therefore if you have any allergies to such please do not use.
The fact that the maximum CBD content in an oil is limited by the THC present in the herbal material used makes it attractive to add an additional amount of purified CBD to boost the percentage advertised on the label. Unfortunately, the Novel Food Catalogue of the EU states that “extracts of Cannabis sativa L. in which CBD levels are higher than the CBD levels in the plant source are novel in food” [35]. This means that enriching a natural hemp extract with pure (often synthetic) CBD makes it a Novel Food product, with the consequence that it must undergo significant safety assessment prior to being marketed. However, it is still unclear in many EU countries if extracts with no added CBD also fall under this regime.
“CBD inhibits the cytochrome P450 enzymes that break down important psychiatric drugs,” says Blessing. CBD isn’t the only substance that messes with the body’s ability to metabolize these drugs — both St. John’s wort and the humble grapefruit are unfriendly — but CBD is comparatively poorly studied. The way CBD inhibits those enzymes could dramatically raise the levels of SSRIs or opioids in the system, potentially leading to an overdose.

Cannabidiol (CBD) oil is essentially a concentrated solvent extract made from cannabis flowers or leaves that is dissolved in an edible oil such as sunflower, hemp, or olive oil. Solvents used can vary from relatively innocuous organic solvents (ethanol, isopropyl alcohol) to more harmful ones (petroleum-ether, naphtha), or even supercritical fluids (butane, CO2). The exact conditions and solvents applied have a great impact on, for example, the taste, color, and viscosity of the final product. Because many other plant components are co-extracted with the desired cannabinoids present in the herbal material, these are sometimes removed by a treatment known as “winterization.” By placing the extract in a freezer (–20 to –80°C) for 24–48 h, components with a higher melting point such as waxes and triglycerides, as well as chlorophyll will precipitate, so they can be removed by filtration or centrifugation [1]. This treatment can significantly improve the taste and color of the final product.
Unfortunately due to strict FDA regulations I am unable to make claims on our products based on your specific needs, I can however say that CBD is a natural anti-inflammatory and could assist. I can also share our top selling products in each category. Please view the links below:http://cbdoilreview.org/product/elixinol-cbd-oil-extract-x-pen-1000mg/http://cbdoilreview.org/product/endoca-hemp-oil-drops-1500mg/http://cbdoilreview.org/product/elixinol-hemp-oil-drops-regular-300mg/http://cbdoilreview.org/product/elixinol-cbd-hemp-oil-capsules-900mg/https://cbdoilreview.org/product/vape-bright-starter-pack-200-mg/This is also a great link to some pages that you may find helpful https://cbdoilreview.org/cbd-cannabidiol/
The Health effects of cannabis and cannabinoids: the current state of evidence and recommendations for research. National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Health Effects of Marijuana: An evidence review and research agenda. Washington, National Academies Press, 2017.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.
CBD has positive implications in a vast number of illnesses and has been shown to boost general health, hair and skin.  Research isn’t conclusive here, although it is strong, and in the coming years, we are expecting to see more and more evidence.  THC, on the other hand, can benefit other disorders but comes with drawbacks, such as the feelings of being high and possible induction of feelings of anxiety and paranoia and more.
Cannabidiol is insoluble in water but soluble in organic solvents such as pentane. At room temperature, it is a colorless crystalline solid.[44] In strongly basic media and the presence of air, it is oxidized to a quinone.[45] Under acidic conditions it cyclizes to THC,[46] which also occurs during pyrolysis (smoking).[47] The synthesis of cannabidiol has been accomplished by several research groups.[48][49][50]
My mother has been on pain killers for a failed diagnosis of lymphoedema. After the third day of using this topical on her right arm, the affected area, she has gotten rid of the pain killers and started sleeping better after 2 months of no sleep. She couldn't believe it and neither could I. I just ordered the oils and will most definitely post her successes. Truly satisfied with your product and I hope that the oils are exactly what she needs! ? thank you
CBD, known scientifically as cannabidiol, is the second most commonly occurring cannabinoid within the marijuana plant, ranking in just below THC, or tetrahydrocannabinol. What is unique and distinctive about CBD, unlike THC this component produces zero psychoactive effects, meaning that it does not create the typical high and euphoria that is linked with marijuana. Furthermore, it has proved to generate immense healing and a multitude of medically beneficial abilities. CBD helps pain on an anatomical level by directly targeting the body’s endocannabinoid system (ECS), which naturally produces some cannabinoids on its own, known as endocannabinoids.
This is precisely why we here at Premium Jane do not advertise “CBD cream for arthritis for sale.” While it may be true that cannabidiol has displayed pain-relieving and anti-inflammatory effects in numerous scientific studies, will still maintain the notion that transparency is the most important thing we can offer to our customers. Those companies who blatantly urge you to buy CBD pain cream for arthritis are simply being deceptive, and not taking into consideration the current FDA status of cannabidiol as a medicine.
When you mix the benefits of coffee and the benefits of CBD oil, you get an incredible morning regime that is good for your whole body! It really is a match made in heaven. Although coffee has many benefits, the caffeine can increase stress hormones called cortisol. However, CBD oil can cause drowsiness in some people. Therefore, when you combine the two to create CBD coffee, you get the best of both worlds.
It’s not about quality, either; even the finest CBD-infused coffee won’t change the mind of substance purists like myself. Let’s say you’re drinking CBD coffee to relax—hey, that’s great… but that caffeine isn’t going anywhere. In fact, the only feasible situation CBD coffee would work would be if the coffee in question was decaffeinated… but we all know that only dads drink decaf. CBD coffee is the culmination of two great things Frankenstein’d together to make one mediocre product, like Julian Lennon or those shoes that look like socks.
CBD products have become increasingly popular in recent years, as more and more producers market CBD as the new "it" drug for the health and wellness set — one that has been touted as a pain reliever and a treatment for anxiety, among other potential applications. Last year, consumer sales of CBD products topped $350 million in the United states, more than triple the amount sold in 2014, and various estimates predict the market could reach $2 billion within the next two to four years.
My mom is late stage dementia. We have tried coconut oil/black pepper/curcumin combo for years. Gives only tine bit of help, and is not something that reverses dementia. Maybe in someone who can score better than a 14 on the mme it could be of help. But cannabinoid is a different story. Cannabinoids produce better results in less time. Can't say yet that they will reverse anything though.
Natural, legal and with no major side effects (so far), CBD is a marketer’s dream. Hemp-based health products are launching left, right and centre, cashing in while the research is in its first flush of hazy potential. As well as ingestible CBD (also sold as hemp or cannabis oils or capsules) the compound has become a buzzword among upmarket skincare brands such as CBD of London. Predictably, Gwyneth Paltrow is a proponent of the trend, and has said that taking CBD oil helps her through hard times: “It doesn’t make you stoned or anything, just a little relaxed,” she told one beauty website.
CBD Topicals are topically applied creams, balms, lotions, salves and other ointments for the skin. From transdermal CBD creams to targeted topicals or salves, CBD Oil Solutions offers a wide range of CBD Oil Topicals. The products contain an active amount of Cannabidiol and cannabinoids that have shown a wide range of benefits both to the skin externally and the muscles, tendons and joints below the surface. 
So far, by far the best medicinal relief I have found for my symptoms is a particular strain of cannabis flower called Harlequin — it contains an almost 3:1 ratio of CBD:THC, which is extremely rare and unique in the cannabis world. There are multiple studies you can find online showing the SYNERGISTIC effects of CBD combined with THC. When they are used together, they are much more medicinally effective than either one is on their own. Most cannabis strains today have zero CBD because growers realized everyone just loves their THC, but the Harlequin strain is a god send.
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