Food and beverage products containing CBD were introduced in the United States in 2017.[54] Similar to energy drinks and protein bars which may contain vitamin or herbal additives, food and beverage items can be infused with CBD as an alternative means of ingesting the substance.[55] In the United States, numerous products are marketed as containing CBD, but in reality contain little or none.[56] Some companies marketing CBD-infused food products with claims that are similar to the effects of prescription drugs have received warning letters from the Food and Drug Administration for making unsubstantiated health claims.[57]
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I have a brother in law who has been diagnosed with cataplexy and narcoplexy, where he starts quivering and slowly loses control of his body and goes into a sleep, which causes him to drop to the ground with mild seizures while he is out. He lives alone (59 years old), but has smoked cannabis since he (we) were teenagers. He still smokes, and is on medication twice a day for this condition, but if he misses those meds by even half an hour, he is at risk of these seizures. The sad part is, these seizures are usually brought on by the smallest emotional change, usually tension, excitement or, the worst thing, if something he finds funny and is the least bit tickled about and starts to laugh, this process will immediately begin. Does anyone know if this kind of condition is treatable with cbd oil’s or concentrates? As I said, he smokes weed, and often grows his own, but he does it for the high and relaxation advantage, since he is basically home-bound due to this condition ending his work career about 4 years ago. Thanks for any replies. I’d be overjoyed if I could tell him there’s a possible solution to the problem other than his prescriptions. Or even if it worked WITH his meds to keep from having to live such a sedentary life.

CBD Oil Drops


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An important factor is the quality and purity of our CBD. We chose the Kentucky farm collective because of the quality of the hemp plants being grown under the Federal Farm Bill and in conjunction with the Kentucky Agricultural Department Hemp Pilot Program. There are very specific guidelines for planting, growing and the processing of the CBD isolate. As a result, the quality of the CBD produced from the whole plant is some of the purest available. We take great pride in providing our clients with an extremely pure, clean and high-quality product to those who desire CBD. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.

Cannabidiol, or CBD for short, is a phyto-cannabinoid found in cannabis plants. However, it does not cause the same psychoactive effects as other naturally occurring cannabinoids (such as tetrahydrocannabinol, or THC). CBD induces feelings of sleepiness and tranquility, making it suitable for insomnia and other sleep disorders; CBD can be used to alleviate symptoms of epilepsy, diabetes, and anxiety disorders, as well. Legality is an issue for some; all 50 states have laws governing the sale, possession, and use of CBD, and they vary significantly (see the table below for a full analysis).
Now, while CBD derived from hemp or psychoactive cannabis (“marijuana”) is chemically identical, there may be reasons other than legal concerns to make the distinction. If the hemp in question is low in CBD as well as THC, it may take exponentially more hemp than marijuana to produce the same amount of CBD. So this raises concerns about concentrates of pesticides and other contaminants getting into CBD oil made from hemp — especially hemp that has traditionally been grown for industrial purposes, and under standards developed with that in mind. In the case of places like China, even those standards may be too lax or not enforced at all.
Outside of CBD I would ask however have you tried having him change his diet? If the IBS is food allergen related, as some studies are starting to show, CBD and the like are only effective at calming some of the symptoms. The most effective treatment is aimed at figuring out what is causing the issues to begin with by starting a food diary and instituting dietary changes. Look into a diet called “The Whole 30” to see if it’s a particular food or food type that is causing aggravation of symptoms. For many people things like Gluten, Dairy, Meat, and/or processed foods are the offending culprits and cutting these out of the diet can result in greatly reduced symptoms and improved quality of life.
CBD oil derived from whole-plant marijuana has seen promising results for numerous medical treatments, including treating children with epilepsy. (In 2013, CNN’s Dr. Sanjay Gupta introduced the world to a child who after using CBD oil went from having 300 seizures a month to only two.) On April 19, the AP reported that an FDA panel is reviewing a a pharmaceutical-grade CBD oil made from whole-plant marijuana called Epidiolex, a possible treatment for rare forms of pediatric epilepsy. If approved, it would be the first marijuana-made medication sold on the U.S. market. A day later, on the marijuana community’s “high holiday,” April 20, New York Senator Chuck Schumer introduced legislation to decriminalize marijuana on the federal level. Forecasters are predicting that legal cannabis in the U.S. will be outselling soda by 2030.

“Placebo response always needs to be taken into account for any treatment being studied,” says Baron. “Placebo response is actually quite high in many pharmaceutical trials, for example. In fact, there are many treatment trials for various medications and other treatments where benefit responses to placebo are actually higher than the treatment itself being studied.”


Selective breeding of cannabis plants has expanded and diversified as commercial and therapeutic markets develop. Some growers in the U.S. succeeded in lowering the proportion of CBD-to-THC to accommodate customers who preferred varietals that were more mind-altering due to the higher THC and lower CBD content.[58] Hemp is classified as any part of the cannabis plant containing no more than 0.3% THC in dry weight form (not liquid or extracted form).[59]

High-CBD strains tend to deliver very clear-headed, functional effects without the euphoric high associated with high-THC strains. They’re typically preferred by consumers who are extremely sensitive to the side effects of THC (e.g., anxiety, paranoia, dizziness). A high-CBD strain would also be a great choice for someone needing to medicate throughout the day to control pain, inflammation, anxiety, or other chronic conditions.

CBD oil extracted from hemp — no matter how it’s consumed — works with the body’s ECS system to replenish cannabinoids and regulate homeostasis. The substance is also anti-anxiolytic, meaning it reduces feelings of anxiety — a common source of sleep problems in adults. For these reasons, hemp-based CBD oil can be highly beneficial for people with insomnia whether they struggle with sleep onset (falling asleep) or sleep maintenance (staying asleep). In addition to insomnia, CBD oil may lead to improvements for the following sleep disorders:
Leafly is the world’s largest cannabis information resource, empowering people in legal cannabis markets to learn about the right products for their lifestyle and wellness needs. Our team of cannabis professionals collectively share years of experience in all corners of the market, from growing and retail, to science and medicine, to data and technology.
A 2017 article published by the National Academies of Sciences, Engineering and Medicine conducted a study in which the results concluded, “In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.” This statement is quite a massive development for the increasing of tolerance towards CBD and CBD based products.
Both CBD oil and CBD cream products have their own unique and significant uses throughout the medical world. They are both highly capable of healing and diminishing pain plus daily discomforts. This all-natural alternative to conventional medications is reasonably affordable and does not produce any of the psychoactive or “high” effects that traditional marijuana flower can, meaning that CBD could be consumed any day of the week at any time of day, leading to its extreme versatility and convenience.

The term "CBD" is a nickname for cannabidiol, which is one of several cannabinoids, or chemical compounds, that are found in cannabis and hemp plants. Of course, the most famous cannabinoid is tetrahydrocannabinol, or THC, which is the main psychoactive component in marijuana (aka, the part that gets you high). Because CBD is not psychoactive, it does not create the same buzzy effects typically associated with marijuana when ingested.


It is for this reason that all the finished hemp goods that you see for sale in America, from food products to clothing to building materials, are part of an imported hemp industry that has surpassed $688 million annually. The size of this import industry is one of the major catalysts for hemp legalization in the U.S. As a renewable source of a range of products, hemp provides an exciting new step in American agriculture.
There has been a fair amount of confusion surrounding the legality of CBD oil. But while the vast majority of cannabinoids are controlled substances under the Misuse of Drugs Act, rest assured that CBD oil is legal across the UK for medicinal purposes, provided it has been derived from an industrial hemp strain that is EU-approved. These strains contain very little to no THC (the psychoactive cannabinoid).
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.
Topicals are applied right to trouble areas so that the CBD oil can work directly where it’s needed most. Ingesting CBD products orally causes CBD and other compounds to enter the bloodstream, which elicits full-body effects and takes up to 2 hours or more before those effects are experienced. With CBD topicals, the healing compound and other hemp-derived nutrients are almost immediately absorbed directly through your skin, allowing them to target the affected area for quicker and more focused effects.  
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The limited studies out there indicate that CBD has, in its various interactions with the brain and immune system, some anti-inflammatory and anti-anxiety effects. It can balance out the effects of THC by reducing the anxiety THC sometimes brings, and many in the industry are big on “broad spectrum” or “full spectrum” configurations, which use many cannabinoids at once.
Two dermatologists I consulted with, New York-based Whitney Bowe, MD and New Jersey-based Jeanette Jacknin, MD, both agreed that CBD’s anti-aging and anti-inflammatory benefits are clinically proven. “Studies have shown that the cannabinoids like CBD in marijuana are anti-inflammatory and anti-aging and topical CBD has proven helpful for acne, eczema, and psoriasis,” Jacknin told me. “Hemp seed oil is reputed to be the most unsaturated oil derived from the plant kingdom, so it is less pore clogging but a great moisturizer for dry, cracked skin.”

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I LOVE my CBD pain cream. It is called “CAD” (short for Carter’s Aromatherapy Designs) cream. The downside is that it’s uber expensive ($45 to $140, for a 2 ounce jar, depending on the strength), but the little jar does seem to stretch quite a way. It smells of peppermint, not skunk. I’m currently experimenting with making my own from home-grown AC/DC. So far, I like the CAD better.
I’ve been hoarding Girl Scouts Thin Mints lately (they’re especially good if you freeze them)—the chocolate is fine, but the peppermint oil is what makes them addicting enough to go through a whole sleeve without getting sick of them. I’m also trying to cut down on sugar, though, and while it would be a huge stretch to say that this peppermint oil-infused clear lip balm is a direct replacement for Girl Scout cookies, it really does have a very satisfying full-mouth taste of peppermint. The CBD oil, which soothes and facilitates healing at the same time, makes this formula an ideal balm for outdoor enthusiasts and or just those who are prone to painfully chapped lips. For those of us with long-hair-don’t-care, it’s not sticky—as a matter of fact, the formula is on the stiff side and won’t cause your hair to stick to your face, a welcome departure from many balms.

The next morning, I blended the contents of the bottle up with collagen (because I add Vital Proteins to pretty much everything I drink) and took my first sip. I was immediately impressed with the taste—so creamy, dreamy, delicious, and not at all skunky. Settling into my couch with my laptop (lazy Sunday mornings are when I like to get myself organized for the upcoming work week), I continued to sip. Normally, and as it would for anyone, diving into my inbox, scanning the upcoming week's calendar, and plotting out all my upcoming to-dos sends shivers of nerves and anxiety down my spine. I love my job, but it comes with its fair share of stress. Miraculously, however, I felt calm, cool, and collected. As my fingers skipped away at lightning speed on my keyboard courtesy of that 80 milligrams of caffeine, I didn't have the usual side effect of nerves, jumps, or jitters. I felt good, and on my way home from the gym later that day, I picked up a couple more bottles of Kickback. What can I say? I was high for it. Of course, "high" not to be taken literally, as CBD—aka cannabidiol—is a non-psychoactive compound of cannabis.


Though clinical and anecdotal evidence suggests CBD’s benefits in managing different conditions, it became most famous for treating a rare and debilitating form of pediatric epilepsy. Dravet’s Syndrome is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day, that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets, and brain surgery, but all have mixed success rates.

CBD topical cream offers a unique cannabidiol delivery system that allows users to administer the active CBD compound directly to the site of discomfort for the most acute, fastest-acting effects possible. At Premium Jane, our infused CBD salves for sale are made from the same expertly sourced hemp extract as our top-shelf CBD oils and capsules. Moreover, our products are 100% USA-made using organic, non-GMO hemp from regulated Pilot Research farms in Oregon; when you buy topical CBD cream from Premium Jane, you are truly getting one of the most expertly-crafted CBD creams on the market.
An excellent example is the use of CBD (and also THC) products for the self-medicating of cancer, with the intention of fully curing it [15]. This is based on an increasing body of preclinical evidence showing cannabinoids to be capable, under some conditions, of inhibiting the development of cancer cells in vitro or in vivo by various mechanisms of action, including induction of apoptosis, inhibition of angiogenesis, and arresting the cell cycle [16]. This is certainly exciting news, and research is ongoing around the world, but there is no solid clinical evidence yet to support that cannabinoids – whether natural or synthetic – can effectively and safely treat cancer in actual humans [17]. In fact, there are indications that certain types of cancer may even accelerate when exposed to cannabinoids [18]. This becomes problematic when patients choose to refuse chemotherapy treatment because they firmly believe in the rumored curative properties of cannabinoids. As a result, recommendation of cannabinoids for treating cancer should be done with great care, and with distinction as to the type of cancer being treated [19].

Cannabis has been used for centuries to treat nerves and anxiety, as well as other mood problems. CBD may help to improve both depression and anxiety, at least in part through its interactions with serotonin receptors in the brain. Research shows that CBD can reduce both mental and physical symptoms of anxiety. A study of CBD given to people before a public-speaking event indicates that CBD can help reduce stress—this and other research has shown that CBD can be an effective treatment for social anxiety.

During one study, 10 healthy male participants took just one 600 mg dose of CBD oil. Their resting blood pressure went down successfully. These same men were then put on stress tests. These tests were specifically designed to raise blood pressure. After taking the same dose of CBD, the men yielded positive results. Their blood pressure was lower than it normally would be in these stressful situations. Most scientists agreed that CBD lowers blood pressure because of its ability to help reduce anxiety and stress.
The 2016 European Journal of Pain conducted a study on rat models to test the effectiveness of CBD against arthritis in order to see if it could serve as an all-natural alternative to the typical arthritis pain medications, which are often tied with numerous uncomfortable and frustrating side effects. The rats were treated for 4 days with 4 different doses of CBD gel, and the results were quite staggering.
Once the oil has been applied, massage it gently but firmly into your skin. The body won’t absorb much of the cannabinoid in small doses, so be sure to apply liberally. Once you’re done, make sure you wash your hands so you do not inadvertently spread potentially irritable substances to sensitive areas. Some oils contain substances that may cause discomfort and irritation to the wrong parts of the body, such as the eyes.
Figuring out how much CBD oil to take can feel like trying to navigate through a complicated maze. The sheer volume of CBD brands on the market can create confusion for consumers, and when you take a closer look, it’s not difficult to understand why. Not only do vendors use different source materials (CBD-rich cannabis vs. industrial hemp, different strains, etc.), but they also implement different extraction techniques .

A CNN program that featured Charlotte's Web cannabis in 2013 brought increased attention to the use of CBD in the treatment of seizure disorders.[68][69] Since then, 16 states have passed laws to allow the use of CBD products with a doctor's recommendation (instead of a prescription) for treatment of certain medical conditions.[70] This is in addition to the 30 states that have passed comprehensive medical cannabis laws, which allow for the use of cannabis products with no restrictions on THC content.[70] Of these 30 states, eight have legalized the use and sale of cannabis products without requirement for a doctor's recommendation.[70]
Not only are we all made differently, we each have our own unique history with the use of substances, medications, supplements, and other things we put in our body. Because of this, we all have different body chemistry, and this will affect how our body reacts to CBD. As R.R Noall over at Herb puts it, “what works for your friend, may not work for you.”
Plus CBD Oil™ products come in a variety of flavors and concentrations to suit your preferences. If you are considering CBD oil for your health, as with any supplement, we encourage you to speak with your physician and dive into the research to learn more about this promising phytonutrient. We at Plus CBD Oil™ are proud of our innovative selection of products.

CBD exists at the confluence of three huge consumer trends. The first is the herbal supplement boom, a $49 billion-a-year industry that has seen rapid expansion since about 2010. The second is the rise of the anxiety economy, in which all sorts of products, from fidget spinners to weighted blankets, are pitched as reducers of the mild panic of everyday life. And the third is the near-overnight creation of a legitimate cannabis industry, thanks to the spread of marijuana legalization.
An important factor is the quality and purity of our CBD. We chose the Kentucky farm collective because of the quality of the hemp plants being grown under the Federal Farm Bill and in conjunction with the Kentucky Agricultural Department Hemp Pilot Program. There are very specific guidelines for planting, growing and the processing of the CBD isolate. As a result, the quality of the CBD produced from the whole plant is some of the purest available. We take great pride in providing our clients with an extremely pure, clean and high-quality product to those who desire CBD. Each and every product that leaves the facility is third-party tested to ensure consistency and quality.
Cost is another consideration. Most CBD oils are sold in concentrations of 300 to 750 mg, although this may range from less than 100 mg to more than 2,000. A good indicator of price-point is the cost per milligram. Low-cost CBD oils usually fall between five and 10 cents per mg; mid-range prices are 11 to 15 cents per mg; and higher-end oils cost 16 cents per mg or higher. Given these varying per-milligram costs, a bottle of CBD oil may be priced anywhere from $10 or less to $150 or more.
CBD Oil, derived from agricultural hemp, has been widely recognized for its many benefits on human health. It has grown in popularity amongst the medical community as a key supplement for maintaining homeostasis. Because CBD oil has the ability to talk to nearly every organ system in the body via the Endocannabinoid System (ECS) this plant-based nutrient plays a key role in optimizing balance and enhancing quality of life.
Disclaimer: This product is not for use by or sale to persons under the age of 18. The statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease. All information presented here is not meant as a substitute for or alternative to information from health care practitioners. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
Some manufacturers ship CBD products nationally, an illegal action which the FDA has not enforced in 2018, with CBD remaining as the subject of an FDA investigational new drug evaluation and is not considered legal as a dietary supplement or food ingredient as of November 2018.[71] CBD is openly sold in head shops and health food stores in some states where such sales have not been explicitly legalized.[72][73]

Of course, there are many different treatments for both anxiety and depression. However, they have a lot of side effects. These include agitation, drowsiness, insomnia, headaches, and sexual dysfunction. In addition, certain prescription drugs can be very addictive, like BZDs. In fact, they can be more addictive than hard drugs such as crack cocaine or heroin.

Fad chasers looking for the next-next big thing may want to check out the CBD-infused ricotta-and-honey toast at Chillhouse, the Instagram-ready coffee shop, nail salon and massage studio on the Lower East Side of Manhattan. And then retreat to Inscape NYC, a meditation and relaxation studio in Chelsea, to unwind with a stress-busting CBD Saturday session.


“I’ve got to be really careful what I say when it comes to preaching about benefits that CBD can bring,” says Richard Roocroft, the vice president of global sales and marketing for Flower Power. “We just say, have a cup of coffee once a day to keep the doctor away.” I ask about his dosage and whether he has information indicating it has any effect. “To answer your question, ‘Do we have the studies?’ No. We have nothing that would support that,” he tells me.
Did you know that 83 percent of Americans drink coffee regularly? In a fast paced world, with the pressures of life pulling us down, it is no wonder we need coffee, but also carry anxiety. Not only does coffee help wake you up in the morning, but it actually has more lot of health benefits than you might realize. However, adding a little CBD oil can increase those benefits even more.

Topicals are cannabis-infused lotions, balms, and oils that are absorbed through the skin for localized relief of pain, soreness, and inflammation. Because they’re non-intoxicating, topicals are often chosen by patients who want the therapeutic benefits of marijuana without the cerebral euphoria associated with other delivery methods. Other transdermal innovations are fast arriving in the cannabis market, including long-lasting patches and tingly lubricants for patients and recreational consumers alike.
The only study that has tested the bioavailability of inhaled CBD is from 2014; it found a bioavailability of about 25 percent for 100 mg and 200 mg doses of CBD using a Volcano vaporizer. (The topical lotions are even less studied; there have been no clinical trials on them at all.) This is more efficient than ingesting CBD, in the same way that vaporizing THC is more efficient than eating it. To get an effect, you should ingest a different amount of CBD than you’d inhale ... but how much is that? How much is too much?
Currently, the only official, FDA-approved use of CBD is as a component in a drug named Epidiolex, which will be used to treat severe forms of epilepsy in children and adults, and which will be, Carson hopes, available to patients by the end of the year. Carson says he developed an interest in CBD because parents of kids with epilepsy came to him having read about CBD’s potential benefits on the internet. “There’s lots of data now that I think really supports that CBD helps for epilepsy,” particularly in reducing the frequency of seizures, he says. Anecdotally, he noticed that the same parents reported another potential benefit associated with CBD: reduced anxiety. “I got the sense that some children did get benefits in terms of anxiety, and I think that’s where I wonder if for example CBD in coffee could potentially be helpful,” he says.
The theoretical logic is there, Gerdeman says. What exactly is that thinking? Well, there are a few different ways CBD could help regulate pain—by increasing your natural endocannabinoids, decreasing your inflammatory response, and desensitizing your pain receptors (although it’s still unclear whether this stands when absorbed topically compared to orally).
^ Klein C, Karanges E, Spiro A, Wong A, Spencer J, Huynh T, Gunasekaran N, Karl T, Long LE, Huang XF, Liu K, Arnold JC, McGregor IS (November 2011). "Cannabidiol potentiates Δ⁹-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats". Psychopharmacology. 218 (2): 443–457. doi:10.1007/s00213-011-2342-0. PMID 21667074.
Scientifically, the difference between what we refer to as hemp and marijuana comes from the intention the strain was bred for. The main difference between hemp and marijuana is the level of THC in the plant. Hemp has high levels of cannabidiol (CBD) and very low levels of tetrahydrocannabinol (THC). Marijuana is recognized for having high levels of THC and lower in CBD. In order to be considered hemp, the plant must have less than 0.3 percent THC. High levels of THC are responsible for the intoxicating feeling that marijuana is known for.  
Side effects of CBD include sleepiness, decreased appetite, diarrhea, fatigue, malaise, weakness, sleeping problems, and others.[3] It does not have intoxicating effects like those caused by THC, and may have an opposing effect on disordered thinking and anxiety produced by THC.[7][10][11] CBD has been found to interact with a variety of different biological targets, including cannabinoid receptors and other neurotransmitter receptors.[7][12] The mechanism of action of CBD in terms of its psychoactive and therapeutic effects is not fully clear.[7]
I have this issue with neuropathy in my feet and it drives me crazy. Cant’ sleep etc… I tried some high dose CBD cream (myaderm) works really well for me. It didn’t cure anything but this is the only cream I could find that where the CBD actually stopped the pain. I think it’s because of how it’s delivered (transdermally). That seems to get down to business faster then the other ones I tried. I put some on before I go to bed and it allows me to sleep painlessly and I don’t need to take any additional pain killers… my not a doctor but it’s worth a try.
Food and beverage products containing CBD were introduced in the United States in 2017.[54] Similar to energy drinks and protein bars which may contain vitamin or herbal additives, food and beverage items can be infused with CBD as an alternative means of ingesting the substance.[55] In the United States, numerous products are marketed as containing CBD, but in reality contain little or none.[56] Some companies marketing CBD-infused food products with claims that are similar to the effects of prescription drugs have received warning letters from the Food and Drug Administration for making unsubstantiated health claims.[57]
While the CBD latte dosage varies from coffee shop to coffee shop, the range seems to fall between two to 15 drops, or approximately 20 to 30 milligrams, says Blessing. That’s a lot less than what’s been shown to work in clinical trials for various conditions, which makes Blessing skeptical that a CBD latte could produce any noticeable effect. “There’s no evidence whatsoever that a small amount of CBD is actually doing anything at all,” she says. “An analogy I give sometimes is, you wouldn’t take 2 mg of ibuprofen. It doesn’t do anything.”

As a healthcare professional I have realized over the years that most physicians and our healthcare system in general are all set up to focus almost entirely on symptoms and the disease state as a problem to treat, not prevent unfortunately. The training that most physicians receive is almost completely pharmacologicaly focused and consequently they treat patients almost as if they are a car to be fixed rather than as a living breathing being.

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