Rich in CBD, cannabis has been used for centuries to fight illness, improve sleep, and lower anxiety. Today, our understanding of the potential benefits of CBD is growing by leaps and bounds—more and more, CBD is seen as a powerful disease-fighting agent. Thanks to decades of scientific investigation, it’s now possible to get the benefits of CBD in supplement form.
Even so, CBD seems to have found its natural target audience among the vegan-curious creative professionals who cluster in trendy hotels like the James New York-Nomad hotel, which offers a room-service CBD tasting menu featuring CBD-infused meatballs and sriracha-mayo House Tots. Or the Standard hotel outposts in Miami and New York, which sell $50 blood orange-flavored gumdrops by the upscale CBD brand Lord Jones in its minibars.
Now, while CBD derived from hemp or psychoactive cannabis (“marijuana”) is chemically identical, there may be reasons other than legal concerns to make the distinction. If the hemp in question is low in CBD as well as THC, it may take exponentially more hemp than marijuana to produce the same amount of CBD. So this raises concerns about concentrates of pesticides and other contaminants getting into CBD oil made from hemp — especially hemp that has traditionally been grown for industrial purposes, and under standards developed with that in mind. In the case of places like China, even those standards may be too lax or not enforced at all.
Look up Chris Shade (quicksilver scientific) on YouTube, specifically a webinar entitled ‘Cannabidiol: The Full Story pt.2’. He is a brilliant biochemist who has been studying the biochemical effects of cannabidiol. He says that CBD has the potential to be more therapeutic than THC as it up-regulates/down-regulates gene expression in over 400 genes each way (up and down). A great balancer and extremely helpful in treating Lyme, more specifically allowing for more aggressive detoxification of the Lyme and co-infections. There is also considerably symbiosis with heavy metals, molds, EMF’s, etc. so you must also address those aspects. It’s supremely complex and even most Lyme literate docs don’t deal with all aspects. Antibiotics are often counterproductive with persistent Lyme as the spirochetes protect themselves with a biofilm that must be broken down (Interfase Plus). Protocols must be comprehensive in order to make progress. If you have not checked your CD57, do that. It’s a marker for natural killer cells commonly associated with Lyme (a simplistic explanation). The reference range is 100-300. First time I had it checked 2 years ago, it was 48. Despite modest attempts to boost my CD57 with some of the Nutramedix products, I only got 6-7 point increase per year. In April of this year, I got more aggressive with a homeopathic regimen, taking a variety of the Cowden (Nutramedix), Buhner and other products. The next time I checked CD57, two months later, it jumped 70 points… remarkable by any measure. My western blot also went from 2 bands to 5 bands as my body as finally able to mount an antibody response. I can’t say for sure which products had the biggest impact, but if I had to guess, it would be the Biocidin LSF (liposomal) and perhaps DesBio Lyme Plus. But I was also taking Samento, Burbur, Cumanda, resveratrol, glutathione, phosphatidylcholine, NanoMojo, and a variety of other things and a good supplement regimen. There is no one product answer. Cannabinoids can help with the symptoms and support a more aggressive regimen, but addressing the Lyme must be a multi-faceted effort. Be very wary of pulsed antibiotic protocols with doxycycline. It’s not out of the question, but decimating your microbiome is counterproductive.
CBD, or canabidiol is an amazingly useful plant compound that is extracted from the cannabis plant. With volumes of medical science now at its back, this compound has been used effectively for a wide range of needs. These particularly wide-ranging applications are the result of its being a part of the “pleiotropic sedate” group. Compounds in this group are especially unique in their ability to affect and travel along many of the typically closed atomic pathways.
In the last 6 months, I have been experimenting with CBD & THC to treat the aforementioned. It’s been an expensive experiment with some improvement, just not enough relief from the pain. I’m currently using 75 mcg of fentanyl transdermal, 30 mg Oxycodone 5x daily, muscle relaxers, arthritis pills, etc and they still don’t get me out of bed most days.
Online retailers: Most CBD oils are sold through online retailers. These establishments tend to have the widest product range, and many offer free doorstep delivery. Online retailers also frequently post product reviews, allowing buyers to compare different oils based on customer experiences to determine which is best for them. These reviews can also be used to evaluate the retailer based on customer service, delivery, and product quality.
The ointment is made from infusing high-quality cannabis flowers in some kind of quality oil—coconut or olive typically—which extracts the active compounds, either CBD, THC, or both depending on the type of hemp used. This oil is then blended with other therapeutic herbs, like arnica or lemongrass essential oils, that are well-known pain relievers.
“Placebo response always needs to be taken into account for any treatment being studied,” says Baron. “Placebo response is actually quite high in many pharmaceutical trials, for example. In fact, there are many treatment trials for various medications and other treatments where benefit responses to placebo are actually higher than the treatment itself being studied.”
Tracking growing conditions is time-consuming. For vegans and gluten-free folks, this has gotten easier over the past couple of years, but in a budding industry that still has difficulty accepting the medicinal benefits of THC, finding out where your hemp is grown can be hard (see: phone calls, being put on hold, etc). Not only that, but there are very few growing regulations for the growing conditions of hemp, which is a red flag in itself when considering products for medical reasons.
Given the degree to which marijuana and cannabinoid derivative use has been stigmatized in the past, their Schedule I classification as illegal substances, and lack of FDA approval, valid medical research on the effects of CBD isn’t as plentiful as it should be. Much of the anecdotal evidence, however, suggests that CBD’s neuro- protective, analgesic, and anti-inflammatory effects with regard to topical applications are promising.2
Kat’s Naturals offers five non-THC tinctures of varying concentrations: Heal and Naked (1,500mg), Balance (750mg), Metabolize (500mg), and Relax (300mg). All five tinctures are available in 5mL to 30mL containers, which can sustain users anywhere from five days to four weeks, depending on their dosage. Kat’s Naturals tinctures are derived from 99% pure fat soluble CBD isolate and pose no risk for yielding positive results on drug tests. For best results, Kat’s Naturals recommends ingesting three to five drops under the tongue and holding them in place for 60 seconds.
For anyone still stumbling across this article…….try the Harlequin strain if you have access to it. It is close to the ideal 5:2 CBD:THC ratio that studies have shown to work synergistically together for maximum medicinal relief. Neither CBD nor THC is as powerful as the two are together, even though THC is getting thrown under the bus in some places as people try to “compromise” for CBD products in the legalization battle. CBD and THC are partners meant to work together.
There are thousands of unique varieties of hemp. The cultivars used for CBD oil contain significantly higher concentrations of CBD than others. Using these uniquely potent plants, it is possible to extract cannabis oil that contains significant levels of cannabidiol, as well as essential vitamins, minerals, fatty acids, terpenes, flavonoids, and other non-psychoactive cannabinoids.
CBD, one of the more than 100 chemicals in cannabis, is emerging as a popular wellness ingredient. The plant extract, often consumed as an oil under the tongue, is now the featured ingredient in high-end products including coconut oil, body lotion, face serum, olive oil, jam, bath scrub, cold-brew coffee, sports salve, lip balm, infused water, gummy snacks and dog treats. Products' prices vary but may cost about triple what their CBD-less counterparts do.
You guys remember coffee, right? You drink it in the mornings to wake yourself up and drown the urge to crawl back into bed. No matter how you take your coffee—black, sweet, over ice, or up your butt—it can be surmised you’re drinking it to absorb the caffeine. See, when caffeine molecules attach themselves to your A1 receptors, your brain can’t tell the difference between these molecules and a neurochemical called adenosine—the stuff that gets you tired. Thus, your brain fools itself into staying awake—that’s why we drink coffee.
Zuardi, A. W., Crippa, J. A., Hallak, J. E., Bhattacharyya, S., Atakan, Z., Martin-Santos, R., … & Guimarães, F. S. (2012). A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation [Abstract]. Current Pharmaceutical Design, 18(32), 5,131–5,140. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/22716160
The term "CBD" is a nickname for cannabidiol, which is one of several cannabinoids, or chemical compounds, that are found in cannabis and hemp plants. Of course, the most famous cannabinoid is tetrahydrocannabinol, or THC, which is the main psychoactive component in marijuana (aka, the part that gets you high). Because CBD is not psychoactive, it does not create the same buzzy effects typically associated with marijuana when ingested.
For ingested CBD, that fat solubility is a problem. “[Ingested] CBD has a very low bioavailability, something between 6 and 15 percent, which varies between people,” says Blessing. Because ingested CBD is so inefficient at actually getting to the brain to stimulate CB1 and other receptors, the doses shown to be effective have to be very high. “There’s no evidence that doses below 300 mg of CBD have any effect in any psychiatric measure,” says Blessing. “And in fact, dose-finding studies show that the lowest clinically effective dose of CBD for reducing anxiety is 300 mg.” Blessing is talking about induced anxiety in otherwise healthy patients, which is all we have studies on; studies of CBD’s efficacy in treating clinical anxiety, which would require regular doses, haven’t been published.
The legal status of CBD in the USA is extra complicated, because many individual states have introduced their own medicinal or even recreational cannabis laws, while the Federal Government does not accept any consumption of cannabis . In the USA , but also in Germany and the UK , CBD has been technically classified as a new medicine, requiring manufacturers to meet much stricter safety, quality, and effectiveness standards. The statement that CBD is simply “legal in all 50 US states” is therefore misleading, if not untrue. It should be noted that even in places where CBD is technically illegal, products may still be easily available because the authorities are lax about enforcing the law, or discussions are still ongoing on how to deal with the influx of CBD. In short, whether CBD is legal depends of how it was made, what is in the final product, and where you are located.
“Research shows that CBD content decreases when it is exposed to heat. It’s likely that the reduction in efficacy is due to the lower content. For instance, studies show that 71 degrees F can accelerate the degradation of CBD in a solution, resulting in less CBD. Potentially adding CBD to hot coffee may degrade it and reduce the amount of CBD available for absorption."
But one of the big differences between CBD and THC is, according to Jane West, cannabis activist, entrepreneur, and founder of the marijuana networking group Women Grow, that CBD is non-intoxicating. “Its potential benefits come with few or no adverse effects,” West tells MarieClaire.com. “So really, this is something that everyone, even those who are reluctant to consume cannabis, can try to incorporate beneficial cannabinoids into their lives without any sort of high or residual THC in their bloodstream.”
First off I’m shocked at all you people in the so- called cannabis industry think there’s some new type of cannabis out there called hemp there’s three types of cannabis…. cannabis ruderalis, cannabis Indica, Cannabis sativa, there’s no new strain called hemp. It’s not cannabis or hemp or marijuana that gets you high it is THC before you post stuff you should do a little more research and I’ll tell you what this is all about just like I said for 5 years with everyone disagreeing its GW Pharmaceuticals say goodbye to all extracts and normally it’s three hundred bucks an hour that was 4 minutes it’s on the house
I just wanted to say… Bullshit!! I just had my second seizure last week. My former coworker’s cousin died from just his first one just last month. It’s just hemp damnitt! If this state isn’t going to fight for it’s people than it’s people have no business fighting for it! “Give me liberty or give me death,” like the twisted forefathers. -S.M. Black
The ECS is responsible for regulating many systems in the body, such as the limbic, metabolic, nociceptive, and immunologic functions. Endocannabinoids are natural chemical regulators in the body that interact with cannabinoid receptors and help maintain homeostasis. They seem to do this by detecting and regulating pain, mood, hunger, memory, and more.
Due to its wide variety of medical benefits, CBD is used to treat a number of common conditions, including chronic pain, inflammation, seizures, insomnia, spasms, multiple sclerosis, and mental disorders such as anxiety and depression. As a topical agent, CBD oil can be directly applied to certain areas of the body as an effective means of relieving pain and soreness, reducing inflammation, and soothing inflammatory skin conditions such as psoriasis, dermatitis, and eczema.
The CDPH memo adds to the confusion by drawing a distinction between “hemp” and “cannabis” — even though hemp is a form of cannabis. If it weren’t, you wouldn’t be able to derive CBD from it. Avoiding this confusion is part of the case for not purging the word “marijuana” from the English language, despite the stigma increasingly associated with the word.
Further explanation is in order. The difference between psychoactive cannabis (“marijuana,” by the increasingly disfavored traditional term) and hemp is a question of THC content — and legal classification. The federal government defines hemp as cannabis with 0.3 percent THC or less in terms of dry weight. The 2014 federal Farm Bill legalized state pilot programs for hemp, and 40 of the 50 states now have defined industrial hemp as distinct from cannabis and removed barriers to its production — including California. However, California’s hemp pilot program is overseen by the California Department of Food and Agriculture (CDFA) — not either the CDPH or Bureau of Cannabis Control.
In the United States, the CBD drug Epidiolex has been approved by the Food and Drug Administration for treatment of two epilepsy disorders. The U.S. Drug Enforcement Administration has assigned Epidiolex a Schedule V classification while non-Epidiolex CBD remains a Schedule I drug prohibited for any use. CBD is not scheduled under any United Nations drug control treaties, and in 2018 the World Health Organization recommended that it remain unscheduled.
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.
The few CBD studies out there give us limited information, and hardly any about recreational CBD use. One study gave people different amounts of ingested CBD (100, 300, and 900 mg), as well as, for comparison, a placebo and Klonopin; those people then had to give a public speech, an action associated with high levels of anxiety in the broad populace. Neither 100 mg nor 900 mg, nor the placebo, had any effect. The 300 mg dose, though, did have a measurable calming effect on heart rate, blood pressure, and anxiety. (The Klonopin also worked.)
CBD creams are produced with the extracted oils from cannabis or hemp infused into a topical base. They act upon the body’s naturally occurring CB2 receptors by binding with these components. The CB2 receptors are activated by either the body’s own, already present endocannabinoid system (ECS), or through the presence of phytocannabinoids, which are typically in the form of either CBD or THC.
Unlike with THC, CBD’s effects aren’t limited to that single receptor. These effects are not precisely known, though CBD certainly has some impact on CB1’s sister receptor (CB2) as well as a receptor called 5-HT1A. When the 5-HT1A receptor comes into contact with a material that agonizes it, the effects can include reduced anxiety and increased calmness.
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In the US you cannot be fired for the use of legal products. Check your local laws but I’m pretty sure CBD-only products are legal in all 50 states because they contain no THC or a negligent amount of it. That being said, if you are taking very high doses of CBD it is possible for a very small amount of THC to be detected, but this would be considered a false-positive result.
Hi, Congrats on finishing chemo & radiation that’s awesome!! I wish you the best of luck!! I was actually wanting to know about dosage for cancer as well..My parents both have recently been diagnosed with cancer 4 months apart and are currently going thru chemo together. I have tried looking for the dosage info but can never find what i’m looking for..I want to try to help lesson the chemo side effects and hopefully kill some of the cancer cells. Can someone please help us?Thank You Christy
CBD topicals include balms, salves, lotions, and oils that are infused with active cannabinoids and are applied to and absorbed directly through your skin. These cannabinoid-infused topicals have become a heavily demanded commodity in both the beauty and medicine worlds thanks to their soothing and rejuvenating effects. The popularity of topical CBD products has grown massively in recent years, with CBD and other cannabinoids making their way into various skin creams, lip balms, shampoos, and more. Choosing a topical can be overwhelming, so we’ve rounded up our ten best CBD products to get you started:
I think being safe to eat is a moot point. These are topical products. I don’t think anybody is buying to eat them. It’s just a marketing tactic. In regards to the chapsticks, unless you were trying to literally eat the chapstick I think whatever negligible amount may make it past your lips and into your mouth, would certainly not be a health concern from any of these products. What concerns me more is there is zero efficacy with all of these products. Do they just decide over breakfast how much CBD needs to be added for the dosage to work? It’s ridiculous that they are marketing it as safe to eat, and people are buying into that bs and providing no clinical studies or research at all. Just my 2 cents
Not only that, but the growing conditions for hemp aren’t federally regulated, which makes it very difficult to know when you’re getting a high quality, clean, and safe product. Knowing the growing conditions of the soil, overall environment, and extraction methods is going to be crucial when hemp-based CBD oils become legal, because it’s been known to absorb toxic spills, pesticides, and other dangerous chemicals that you don’t want to be ingesting.
I suffer fr migraines. Currently having Botox injections every three months for the last three years. This has helped went fr 24 to 30 migraines a month to 6 to 8 , now I'm back up to 14 to 20 a month. My doctor thought CBD oil might help. I have also started having anxiety attacks for a year now. I'm really confused with the dosages. Any thoughts would b helpful
I have read that ACDC is good for tremors. It has not been easy to find, so I can’t give my experience yet. I have noticed an improvement in my typing since I started my CBD capsules. Also my clients have commented that I don’t shake as much. A company in Calaifornia called CannaKids carries a oil in a syringe that is made from ACDC and they use it to treat cancer in children. You could put that in a capsule if you don’t want to just eat it. I just used some right now.