High-CBD strains can be smoked or vaporized for immediate effects with little to no high, depending on the strain’s THC content. A strain may contain only trace amounts of THC for clear-headed relief, or it may have balanced levels of THC and CBD, delivering a mild high but potent relief. Explore the menu of your nearby dispensary for a full list of the offerings near you, or browse high-CBD strains on Leafly for an idea of popular varieties to look out for.
“CBD inhibits the cytochrome P450 enzymes that break down important psychiatric drugs,” says Blessing. CBD isn’t the only substance that messes with the body’s ability to metabolize these drugs — both St. John’s wort and the humble grapefruit are unfriendly — but CBD is comparatively poorly studied. The way CBD inhibits those enzymes could dramatically raise the levels of SSRIs or opioids in the system, potentially leading to an overdose.
If you read the ingredient list, often everything in the jar is straight from mother earth. As long as that's indeed the case with the cream you have your eye on, the formula is immensely safe, chemically, says Gregory Gerdeman, Ph.D., neurophysiologist who researches cannabinoid biology and pharmacology at Eckerd College in Saint Petersburg, FL.. And since they're formulated to be topical—absorbing into the top layer of skin—and not transdermal—which would pass through the skin and into your bloodstream—there's no risk of getting high, Gerdeman explains. (P.S. Here's How Marijuana Affects Athletic Performance.)
The limited studies out there indicate that CBD has, in its various interactions with the brain and immune system, some anti-inflammatory and anti-anxiety effects. It can balance out the effects of THC by reducing the anxiety THC sometimes brings, and many in the industry are big on “broad spectrum” or “full spectrum” configurations, which use many cannabinoids at once.
It’s not about quality, either; even the finest CBD-infused coffee won’t change the mind of substance purists like myself. Let’s say you’re drinking CBD coffee to relax—hey, that’s great… but that caffeine isn’t going anywhere. In fact, the only feasible situation CBD coffee would work would be if the coffee in question was decaffeinated… but we all know that only dads drink decaf. CBD coffee is the culmination of two great things Frankenstein’d together to make one mediocre product, like Julian Lennon or those shoes that look like socks.

However, bear in mind that if you’re looking for CBD muscle rub for sale online, products can come in a variety of different formats (some of which are better than others). With Premium Jane, though, you are getting an ointment that has been sourced from the country’s most potent industrial hemp supply and laboratory-verified for purity and CBD content – meaning no second-guessing as to whether or not the cream actually contains therapeutic cannabidiol.

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