This is a topic I am asked about all the time, and have been for years: how does cannabis help sleep and health? I’ve heard that the number-two reason why people smoke or use cannabis is for sleep. Considering the recent passing of the recreational use of cannabis in California and other several states I think it is high time (pun intended!) to look at understanding CBD, one of the most active ingredients in medical cannabis.

Hi Colleen, it's almost a year later and I'm wondering how you're doing. I'm experiencing a recurrence of Stage 3 ovarian, originally diagnosed in 2011. I've decided to get some chemo, not sold on another 6 cycles though. As a new MMJ patient, I'm still going to go through with Rick Simpson Oil (THC+CBD,) and I just joined a program with my local dispensary to get CBD capsules for $2 each when I order them at least 30 at a time. I hope you're doing well!! I'm off to do more research on dosing. **NOTE: If you have ANY experience with CBD treatment of ovarian cancer, PLEASE respond. Thank you!!
CBD is short for cannabidiol, and it is one of more than 60 compounds found in these plants.  It acts on the body’s endocannabinoid system, creating physical changes in the body, which can be beneficial in many ways.  In recent times, it has become increasingly understood that taking CBD oil, a product made from CBD, can have a positive influence on many aspects of life and health.
Cannabis oil, whether CBD, THC, or both, is extracted from flowers, leaves, and the stalk of the plant mainly using different solvents – butane, CO2, ethanol, petroleum ether, naphtha, olive oil, or whole plant extraction (that makes Rick Simpson Oil). Depending on whether you’re extracting oils at home or getting them from a licensed producer, the process ranges from simple to incredibly complex.
Once applied to a targeted area, a CBD topical penetrates and affects the CB2 receptors. Topical applications absorbs into the skin slowly supplying medicine over a period of time. This means you can get all the healing effects of CBD during a longer timeframe. The CB2 receptors are throughout the body and will activate either naturally by the endocannabinoid system or from phytocannabinoids like CBD and THC. The active cannabinoids are absorbed into your skin to signal the receptors to provide relief.
The legal status of CBD in the USA is extra complicated, because many individual states have introduced their own medicinal or even recreational cannabis laws, while the Federal Government does not accept any consumption of cannabis [32]. In the USA [33], but also in Germany and the UK [34], CBD has been technically classified as a new medicine, requiring manufacturers to meet much stricter safety, quality, and effectiveness standards. The statement that CBD is simply “legal in all 50 US states” is therefore misleading, if not untrue. It should be noted that even in places where CBD is technically illegal, products may still be easily available because the authorities are lax about enforcing the law, or discussions are still ongoing on how to deal with the influx of CBD. In short, whether CBD is legal depends of how it was made, what is in the final product, and where you are located.
Fast-forward a couple days and a couple bottles of the aforementioned CBD coffee later, and I was 100% sold. My wallet, however, was not. Kickback is supremely formulated with organic, high-quality ingredients, and justly, the price per pickup runs high. So when I chatted with Byrdie's wellness editor (and unofficial CBD whisperer), Victoria Hoff, the following week, she sparked the obvious idea to make my own. Of course, I love the convenience and hard-to-mimic deliciousness of Kickback, but I could easily create something just as delicious at home with a tincture of CBD oil and my favorite go-to brewing method. She was right, and for the past few weeks, I've experimented with my two favorite tinctures (both are from Charlotte's Web) to create my own anxiety-melting concoctions of coffee. My wallet has felt satisfyingly heavier.
As a healthcare professional I have realized over the years that most physicians and our healthcare system in general are all set up to focus almost entirely on symptoms and the disease state as a problem to treat, not prevent unfortunately. The training that most physicians receive is almost completely pharmacologicaly focused and consequently they treat patients almost as if they are a car to be fixed rather than as a living breathing being.
I’ve been hoarding Girl Scouts Thin Mints lately (they’re especially good if you freeze them)—the chocolate is fine, but the peppermint oil is what makes them addicting enough to go through a whole sleeve without getting sick of them. I’m also trying to cut down on sugar, though, and while it would be a huge stretch to say that this peppermint oil-infused clear lip balm is a direct replacement for Girl Scout cookies, it really does have a very satisfying full-mouth taste of peppermint. The CBD oil, which soothes and facilitates healing at the same time, makes this formula an ideal balm for outdoor enthusiasts and or just those who are prone to painfully chapped lips. For those of us with long-hair-don’t-care, it’s not sticky—as a matter of fact, the formula is on the stiff side and won’t cause your hair to stick to your face, a welcome departure from many balms.
That's not to say CBD-infused creams definitely won't reduce your acute pain or muscle soreness. That's because pretty much all of these creams on the market right now have other scientifically-proven analgesic compounds, like menthol, camphor, and capsaicin which are also found in other, non-CBD topical pain relievers. "Any cream with a heating or cooling sensation desensitizes the nerves to pain by distracting them with stimuli on top," Dr. Colberg explains. Plus you're often massaging the area as you apply, which improves circulation and reduces muscle spasms, he adds.

You only have to read the reviews under a CBD product on the Holland & Barrett website to see the extent to which anecdotal reports cannot be trusted. More than 100 customers gave Jacob Hooy CBD+ Oil five stars, with a few saying they always noticed if they missed a dose (presumably this made them less relaxed, although they did not reveal what they were taking it for), while 93 people gave it one star, saying it did nothing, or was too weak. One couple even said it gave them palpitations and a sleepless night. All these people had different conditions, expectations and situations. “And,” says McGuire, “you have to remember that anything can have a placebo effect.” While it looks unlikely that the recommended doses of these products will do any harm, McGuire’s guess is that doses are so small “that it’s like homeopathy – it’s not going to do anything at all”.


I have this issue with neuropathy in my feet and it drives me crazy. Cant’ sleep etc… I tried some high dose CBD cream (myaderm) works really well for me. It didn’t cure anything but this is the only cream I could find that where the CBD actually stopped the pain. I think it’s because of how it’s delivered (transdermally). That seems to get down to business faster then the other ones I tried. I put some on before I go to bed and it allows me to sleep painlessly and I don’t need to take any additional pain killers… my not a doctor but it’s worth a try.
Another interesting observation was the presence of high levels of non-decarboxylated cannabinoids in multiple samples. It is well known that CBD and THC are not produced as such by the metabolism of the cannabis plant. Instead, cannabinoids are excreted in the form of carboxylic acids such as CBD-acid and THC-acid [52]. The physiological effects of these “acidic” cannabinoids have been studied only to a very limited extent. Only after proper heating (e.g., during smoking, vaporizing, or baking with cannabis) are these natural precursors rapidly converted into the more well-known CBD and THC, respectively. This process is called decarboxylation [52]. Although decarboxylation also takes place during the production of cannabis oils (e.g., during the evaporation of solvents, or during a separate decarboxylation step as part of the production process), 7/46 samples (15%) contained > 25% of its cannabinoid content in the form of acidic cannabinoids, indicating poor control over the decarboxylation process. To address the issue, some producers simply add up the content of CBD and CBD-acid in order to boast a higher “total CBD” content on the label, while advertising this as “raw CBD.”

Be careful to check the nutritional info. On back of bottles. While some brands boast of high mg.s that is for the whole bottle. I use a brand that is 2 oz. 100 mg. Pet dose. A dose is 3 drops. I’ve seen some boast of 700 mg. Or more, but you read on back that a dose is 20 drops for 10 mg. Of help oil. That 700 is the whole 1oz. Bottle and cost twice what I pay for a 2 is bottle.

CBD or Cannabidiol, is the non-psychoactive compound found in the cannabis sativa plant (Industrial Hemp). For many, the health benefits of adding CBD to their diet results in positive effects to the body’s endocannabinoid system – the vast network of CB1 and CB2 receptors and other receptors within the body and system found naturally found in the human body.
“If you’re taking Prozac or some other medication, you really need to think carefully about what you’re doing, because it can harm you, and you should talk to your doctor about it,” says Blessing. Blessing does note that while the drug interactions are potentially very serious, the doses in consumer CBD products are so low that the risk is likely minimal. Regardless, the fact that CBD has drug interactions should indicate that it is, at least sometimes, in some doses, actually doing something.
The legal status of CBD in the USA is extra complicated, because many individual states have introduced their own medicinal or even recreational cannabis laws, while the Federal Government does not accept any consumption of cannabis [32]. In the USA [33], but also in Germany and the UK [34], CBD has been technically classified as a new medicine, requiring manufacturers to meet much stricter safety, quality, and effectiveness standards. The statement that CBD is simply “legal in all 50 US states” is therefore misleading, if not untrue. It should be noted that even in places where CBD is technically illegal, products may still be easily available because the authorities are lax about enforcing the law, or discussions are still ongoing on how to deal with the influx of CBD. In short, whether CBD is legal depends of how it was made, what is in the final product, and where you are located.
CBD oil is most readily available as a tincture. This can be taken by applying a few drops under your tongue, holding in your mouth for a few moments so it can be absorbed, before swallowing. It can also be added to water or smoothies. A spray form is available (simply spritz under your tongue), as are capsules, creams that can be applied topically, and e-liquid for vape pens.
There has been a lot of hype recently, especially throughout the media, regarding the rising-in-popularity CBD, but still plenty of confusion may exist regarding this naturally occurring chemical’s abilities, composition and why exactly it works. Probably the two most common topical forms of CBD are oils and creams, so these are the two products we will be focusing on.
While there are producers who will tell you the difference between legal and illegal CBD comes down to whether your batch is derived from marijuana or hemp—both are plants in the cannabis family, but hemp contains very little THC compared to marijuana—the truth is that even hemp isn’t legal everywhere. In Massachusetts, for example, you’re allowed to grow marijuana at home, but it’s still a crime to grow hemp.
The topical menthol ointment is our most common product for direct application to sore joints, muscle tissue, and damaged skin areas. Standard CBD oil drops can take up to an hour (or longer) to take effect (since they have to enter into the bloodstream), but with topical creams, effects are typically felt within minutes as the active cannabidiol simply has to diffuse across the dermal layers and to the site of inflammation.
Additionally, as many as 26/46 samples (57%) had a THC content > 1%, with one sample peaking at 57.5%. In 18/46 samples (39%) the oil contained virtually only THC (with CBD < 0.1%). Although many of the samples analyzed were purposely made to contain a high THC content, it is unclear whether oil consumers are always aware they are consuming THC, and thereby exposing themselves to the adverse effects of this psychotropic compound, such as intoxication, panic attacks, or disorientation. It should be noted that although the exact legal status of CBD may be debatable, THC-rich extracts are strictly prohibited in virtually all countries.
Out of all the CBD products I’ve tested and used in the past few weeks, this thick green lemon-vanilla scented salve is my favorite. I massage it onto my sore red knuckles after boxing practice, and if it weren’t so expensive, I would encase my entire body in it. The cannabis sativa seed oil in this salve has antioxidant properties so that your skin can repair itself from the inside out, while the thick balm-like formula protects your skin from environmental aggressors. I would not recommend rubbing this onto your face because it’s so thick, but do whatever you want on the rest of your body—and if your feet are in need of some serious TLC in time for summer sandals weather, consider rubbing this onto your cracked heels and putting on a pair of soft socks before bed. The next morning, you’ll have baby’s feet again.
Having run infusion workshops in Denver for the last 3 years, I have played with several recipes. Just Add Herbals has kits that include hypoallergenic mediums that you can infuse with kief, which they give you a way to extract from cannabis. Even lower quality cannabis can be used, the key is to pay attention to the genetic you are using. Kief makes dosing easier and these kits are a simple way to infuse not just salve, but tincture, massage oil, and cooking oil as well. The salve may be ideal for folliculitis – I’d be curious to hear how it does for you.
My mother has dementia/Alzheimers along with a broken knee that they will not repair do to her mental status. She is currently in a nursing home. I firmly believe her mental situation began with the over use of hydrocodone for over 30 years and was acerbated by the trauma of breaking and disconnecting her knee cap. Since weaning her off of her meds (still in progress) we have regained much of her consciousness. I want to try CBD to help in her recovery or to help slow down the disease. I cannot find a dosage recommendation plus the nursing home/doctor does not recommend it. I would need to give it to her when I am there visiting (about 3 - 4 times per week). Is there a recommended dosage for dementia/Alzheimers?
“If you’re taking Prozac or some other medication, you really need to think carefully about what you’re doing, because it can harm you, and you should talk to your doctor about it,” says Blessing. Blessing does note that while the drug interactions are potentially very serious, the doses in consumer CBD products are so low that the risk is likely minimal. Regardless, the fact that CBD has drug interactions should indicate that it is, at least sometimes, in some doses, actually doing something.
Locsta....I share your pain of degenerative and bulging disk disease, along with fibromyalgia, chronic fatigue and arthritis. Absolutely no energy and chronic pain all day, every day. I'm curious as to what type and brand of the CBD oil you are taking and for how long have you been using it? I've been researching CBD oil for months and am quite confused!
While we hope you’ll give our CBD latte a try, making CBD coffee doesn’t have to be complicated. Adding a little flavorful drop of CBD oil to your morning coffee is a simple step to start your day out healthier and happier! Of course, there’s no reason you can’t add it to your afternoon pick-me-up cup, too. Either way, it’s a great step in the right direction.
There is certainly substantial anecdotal evidence that CBD can help treat anxiety, but the scientific evidence remains very limited, says Blessing. “Probably the best evidence comes from studies on anxiety giving speeches, comparing normal subjects, and those with social anxiety disorder,” she says. “The doses that were found to reduce anxiety when someone’s giving a public speech experimentally were[approximately] 300 mg.”
But it’s not just that coffee shops don’t have to be specific about what CBD in a latte is supposed to do, and thus don’t — legally, they can’t. “Once anyone, outside of the one FDA-approved medication, says ‘Hey, if you drink this, it’ll cure your anxiety, or your seizures, the FDA is going to come knocking at that point,’” says Carson. When shops offer CBD-infused products, then, they are relying on the customer — and perhaps the placebo effect — to fill in the blanks.

What makes CBD so appealing is that it’s non-intoxicating, so it won’t get you high, though it “is technically psychoactive, because it can influence things like anxiety,” Jikomes said. Although much of the marketing blitz around CBD centers on the fact that you can take it without getting stoned, there isn’t much research looking at the effects of CBD when used in isolation, with a couple of exceptions. One is the use of CBD to treat seizures: CBD is the active ingredient in the only cannabis product that the Food and Drug Administration has signed off on — a drug called Epidiolex, which is approved for treating two rare forms of epilepsy. Animal models and a few human studies suggest that CBD can help with anxiety, but those are the only conditions with much research on CBD in isolation.
I tell several sellers of CBD food and drink what I learned from Blessing and ask what they think. “Return customers who come back, and swear by it and love it, buy two at a time to stock up for the week because they do find it to be very helpful,” says Tavares. Clancy echoes this: “We rely a lot on consumer feedback and testimonial, and generally it’s positive when taking that minimal amount. Now, that very well could be a placebo effect, but either way, people have come back and reported significant benefits when it comes to easing social anxiety.”
However (and this is very important), as has typically been the case with legal marijuana, the federal government mostly looks the other way while individual states decide how to treat CBD. As such, most states allow CBD products in some form, usually for medical purposes. The 30 states that have legalized medical marijuana include CBD products in that protection, while a number of other states have specific CBD laws that allow for those products in some form, so long as they also contain no more than a miniscule amount of THC. Only four states consider all cannabis-derived products, including CBD, to be illegal: Idaho, South Dakota, Nebraska and Kansas.

Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn

I just wanted to say… Bullshit!! I just had my second seizure last week. My former coworker’s cousin died from just his first one just last month. It’s just hemp damnitt! If this state isn’t going to fight for it’s people than it’s people have no business fighting for it! “Give me liberty or give me death,” like the twisted forefathers. -S.M. Black
I wanted to tell people here that CBD has been very effective for my anxiety, and helps with insomnia. For me, it was a cumulative effect, after a week of one dropper of oil, I can sleep very well at night. I feel like I am not polluting my body with commercial pharmaceuticals. I wish everyone here the best, and hope it works for you as well as it has for me.
Weight plays a role in the effects of CBD oil, and bottle size should be selected based on how much you weigh. Let’s say you weigh less than 130 pounds and desire light CBD oil effects; this means that 11 mg or less will probably suffice per dose, giving roughly 40 doses from a 450-mg concentration. If you weigh more than 230 pounds and desire strong effects, then this same concentration will supply roughly 10 doses. 
If you don't live in a legalized state, you can typically still get CBD-infused creams. Since there's no regulation or standardized testing, your best bet is to find trustworthy brands who use creams free of toxins but with additional pain relievers like menthol, capsaicin, lemongrass, or camphor. Try Mary's Nutritionals Muscle Freeze ($70; marysnutritionals.com) or Elixinol's CBD Rescue Balm ($40; elixinol.com).

Though clinical and anecdotal evidence suggests CBD’s benefits in managing different conditions, it became most famous for treating a rare and debilitating form of pediatric epilepsy. Dravet’s Syndrome is notoriously resistant to current approved treatment methods. Sufferers are plagued by seizures, often up to hundreds a day, that worsen as they age and can be life-threatening. Currently, treatment methods include having the child wear an eyepatch, specialized diets, and brain surgery, but all have mixed success rates.
Let’s not compare what’s happening to hemp to common sense. Let the state try to tell about 90% of the population that CBD is now banned. I see it as an advertisement. Well that and the lawsuit I will be filing in federal court. Once again we have proof that the BCC is in violation of Business Code 26013-14. They have hijacked prop 64 and are systematically gutting and delivering it to the large players. The entire board needs to be fired and replaced with an industry board. The two union members are ok, but the rest got to go. It says a lot when the good part of the board are the unions and the rest are the appointed assassins.
Roocroft explained his company’s low dose by saying, “Everyone’s different, so when it comes to microdosing, they can control their cup of coffee, which is a 6-ounce serving per brew.” He’s not the only person I talked to who used the term “microdosing.” Blessing says he’s misusing the term. Microdosing means using very small amounts of very powerful drugs; sometimes, this can have extremely mild or even totally different effects from what is considered a full dose. But the key is microdosing still has a provable effect.
But, different parts of the cannabis sativa plant, like the flowers, leaves, and stalk, are governed instead by the Access to Cannabis for Medical Purposes Regulations (ACMPR) and the Narcotic Control Regulations (NCR) instead, because its levels of THC and CBD are much higher. Hemp farmers must currently destroy the leaves and flowers in a safe way, but moving forward towards legalization will allow companies and farmers to use the full plant for its’ multiple purposes.

So far, by far the best medicinal relief I have found for my systems is a particular strain of cannabis flower called Harlequin — it contains an almost 3:1 ratio of CBD:THC, which is extremely rare and unique in the cannabis world. There are multiple studies you can find online showing the SYNERGISTIC effects of CBD combined with THC. When they are used together, they are much more medicinally effective than other one is on their own. Most cannabis strains today have zero CBD because growers realized everyone just loves their THC, but the Harlequin strain is a god send.

×